Nichols Larry, Ocque Rebecca Z, Daly Ivonne
Department of Pathology, University of Pittsburgh Medical Center, A610 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA.
Patholog Res Int. 2011 Jan 23;2011:545981. doi: 10.4061/2011/545981.
Zygomycosis is an increasing threat to patients with human immunodeficiency virus (HIV) infection. Zygomycosis (formerly called mucormycosis) is the fungal infection with Mucor, Rhizopus, or other species that share a common morphology of large empty pauciseptate hyphae with rare random-angle branching and a collapsed "twisted ribbon" appearance. Morphology allows a specific diagnosis on frozen section or smear prior to growth and identification of the fungi in culture which makes it improtant because treatment is different than that for more common mycoses such as candidiasis and aspergillosis. We present an informative and illustrative case of zygomycosis in a patient with HIV infection and liver transplantation.
接合菌病对人类免疫缺陷病毒（HIV）感染患者构成的威胁日益增加。接合菌病（以前称为毛霉病）是由毛霉、根霉或其他具有共同形态特征的菌种引起的真菌感染，这些菌种具有大的、空的、少隔的菌丝，罕见的随机角度分支以及塌陷的“扭曲带状”外观。这种形态学特征使得在真菌培养生长和鉴定之前，通过冷冻切片或涂片就能做出明确诊断，这一点很重要，因为其治疗方法与念珠菌病和曲霉病等更常见的霉菌感染不同。我们报告了一例HIV感染合并肝移植患者发生接合菌病的病例，该病例具有一定的参考价值且具有代表性。
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