Uhm Jae-Sun, Hwang Il-Ung, Oh Yong-Seog, Choi Min-Seok, Jang Sung-Won, Shin Woo-Seung, Kim Ji-Hoon, Lee Man-Young, Rho Tai-Ho, Kim You-Ho, Sung Jung-Hoon, Lee Young-Soo, Cho Jeong-Gwan, Oh Dong-Jin, Kim Dae-Kyeong, Namgung June, Park Kyoung-Min, Kim Yong-Hoon, Kim Yoon-Nyun, Lim Hong-Euy, Cha Tae-Joon, On Young-Keun, Shin Dong-Gu, Pak Hui-Nam, Kim Nam-Ho
Department of Cardiology, The Catholic University of Korea, Seoul, Korea.
Pacing Clin Electrophysiol. 2011 Jun;34(6):717-23. doi: 10.1111/j.1540-8159.2010.03024.x. Epub 2011 Feb 17.
The objective of this study was to determine the prevalence of electrocardiographic (ECG) findings suggestive of sudden cardiac death risk in apparently healthy young Korean men.
We administered questionnaires that elicited personal and family histories and performed ECGs on 10,867 male subjects (mean age, 20.9 years). The subjects with abnormal ECG findings underwent echocardiography, a treadmill test, Holter monitoring, a flecainide provocation test, or an electrophysiologic study (EPS) according to the ECG findings and histories.
Of the subjects, 5.95% had left ventricular hypertrophy on ECG, but no subjects had hypertrophic cardiomyopathy by echocardiography. The percentage of subjects with a Brugada ECG pattern was 0.90%. We identified one subject with a positive result on the flecainide provocation test. The percentage of subjects with a preexcitation ECG was 0.17%. In two of the subjects, supraventricular tachycardia was induced in the EPS. Of the subjects, 0.05% had epsilon waves, but there were no subjects with arrhythmogenic right ventricular dysplasia/cardiomyopathy by echocardiography. The percentage of subjects with long QT intervals was 0.02%, but there were no arrhythmias on the treadmill test or Holter monitoring.
The prevalence of a Brugada ECG pattern in apparently healthy young men is higher in Korea than other countries.