Hagey Laboratory for Pediatric and Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Oral Dis. 2011 Sep;17(6):541-9. doi: 10.1111/j.1601-0825.2011.01787.x. Epub 2011 Feb 18.
Wound healing is a complex biological process that affects multiple tissue types. Wounds in the oral cavity are particularly challenging given the variety of tissue types that exist in close proximity to one another. The goal of regenerative medicine is to facilitate the rapid replacement of lost or damaged tissue with tissue that is functional, and physiologically similar to what previously existed. This review provides a general overview of wound healing and regenerative medicine, focusing specifically on how recent advances in the fields of stem cell biology, tissue engineering, and oral disease could translate into improved clinical outcomes.
伤口愈合是一个复杂的生物学过程，影响多种组织类型。由于口腔中存在多种组织类型且彼此相邻，因此口腔伤口尤其具有挑战性。再生医学的目标是以具有功能且在生理上与先前存在的组织相似的组织来促进快速替代丢失或受损的组织。本综述提供了伤口愈合和再生医学的概述，特别关注干细胞生物学、组织工程和口腔疾病领域的最新进展如何转化为改善的临床结果。
