University of Bristol, School of Social and Community Medicine, Oakfield Grove, Bristol BS8 2BN, UK.
Trials. 2011 Feb 19;12:49. doi: 10.1186/1745-6215-12-49.
Depression is common and can have devastating effects on the life of adolescents. Psychological interventions are the first-line for treating or preventing depression among adolescents. This proposal aims to evaluate a school-based, universal psychological intervention to reduce depressive symptoms among student's aged 13-14 attending municipal state secondary schools in Santiago, Chile.
This is a cluster randomised controlled trial with schools as the main clusters. We compared this intervention with a control group in a study involving 22 schools, 66 classes and approximately 2,600 students. Students in the active schools attended 11 weekly and 3 booster sessions of an intervention based on cognitive-behavioural models. The control schools received their usual but enhanced counselling sessions currently included in their curriculum. Mean depression scores and indicators of levels of functioning were assessed at 3 and 12 months after the completion of the intervention in order to assess the effectiveness of the intervention. Direct and indirect costs were measured in both groups to assess the cost-effectiveness of this intervention.
As far as we are aware this is the first cluster randomised controlled trial of a school intervention for depression among adolescents outside the Western world.
ISRCTN19466209.
抑郁症在青少年中较为常见，可能对其生活造成严重影响。心理干预是治疗或预防青少年抑郁的首选方法。本研究旨在评估一种基于学校的、普遍性的心理干预措施，以降低智利圣地亚哥市公立州立中学 13-14 岁学生的抑郁症状。
这是一项以学校为主要单位的集群随机对照试验。我们将该干预措施与对照组进行了比较，涉及 22 所学校、66 个班级和大约 2600 名学生。积极参与的学校的学生参加了 11 次每周和 3 次强化认知行为模式干预课程。对照组学校则接受了其课程中目前已包含的常规但强化的咨询课程。在干预完成后 3 个月和 12 个月评估抑郁评分均值和功能水平指标，以评估干预的有效性。为评估该干预措施的成本效益，我们在两组中测量了直接和间接成本。
据我们所知，这是首次在西方世界以外的国家开展的针对青少年抑郁的学校干预的集群随机对照试验。
ISRCTN86324404。
