马拉维一家中心医院成人肺结核患者维生素 D 缺乏症的流行率。
Prevalence of vitamin D deficiency in adult tuberculosis patients at a central hospital in Malawi.
机构信息
College of Medicine, University of Malawi, Blantyre, Malawi.
出版信息
Int J Tuberc Lung Dis. 2011 Mar;15(3):408-10.
Vitamin D deficiency (VDD) is associated with impaired mycobacterial immunity and susceptibility to tuberculosis (TB). We measured 25 hydroxy vitamin D levels in 161 adult TB patients at a central hospital in Malawi, of whom 120 (74.5%) had ≤75 nmol/l (hypovitaminosis D), 68 (42%) had ≤50 nmol/l (VDD) and 13.6% of in-patients and 6.8% of out-patients had ≤25 nmol/l (severe VDD). In-patients had lower body mass index (BMI; 19.0 vs. 20.5, P < 0.004), and vitamin D levels were lower in those with BMI < 20. However, on multiple regression analysis in-patient status and BMI were not associated with vitamin D level. We conclude that VDD is common in adult TB patients in Malawi. In this small sample, it was not possible to identify any independent associations of VDD.
维生素 D 缺乏症（VDD）与分枝杆菌免疫受损和易患结核病（TB）有关。我们在马拉维的一家中心医院测量了 161 名成年 TB 患者的 25 羟基维生素 D 水平，其中 120 名（74.5%）≤75nmol/l（维生素 D 不足），68 名（42%）≤50nmol/l（VDD），13.6%的住院患者和 6.8%的门诊患者≤25nmol/l（严重 VDD）。住院患者的体重指数（BMI）较低（19.0 与 20.5，P < 0.004），BMI<20 的患者维生素 D 水平较低。然而，在多元回归分析中，住院患者状态和 BMI 与维生素 D 水平无关。我们得出结论，马拉维的成年 TB 患者中 VDD 很常见。在这个小样本中，无法确定 VDD 是否存在任何独立关联。
Zotero 插件