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机器人辅助腹腔镜根治性膀胱切除术治疗老年膀胱癌的可行性和结局。

Feasibility and outcomes of robotic-assisted laparoscopic radical cystectomy for bladder cancer in older patients.

机构信息

Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7235, USA.

出版信息

Urology. 2011 May;77(5):1111-4. doi: 10.1016/j.urology.2010.07.510. Epub 2011 Feb 18.

Abstract

OBJECTIVES

To report our maturing experience with robotic radical cystectomy as applied to an older patient population with regard to perioperative measures and pathologic outcomes. A robotic approach to radical cystectomy for bladder cancer have recently been described, but its application in an older patient population, which is often the case in bladder cancer and cystectomy, has not yet been assessed.

METHODS

A total of 119 patients underwent robotic cystectomy and extracorporeal urinary diversion at our institution from January 2006 through October 2009 for clinically localized bladder cancer. Owing to the patient selection early in the present series, the first 20 cases were excluded. The clinical characteristics, operative outcomes, and pathologic results of the consecutive cases were categorized by age (younger, <70 years vs older, age ≥70 years).

RESULTS

The outcomes of the 61 younger and 38 older patients, including 7 patients >80 years old, were assessed. The younger versus older patients had a lower American Society of Anesthesiologists score (2.6 vs 3.0; P < .001), greater body mass index (28.2 vs 26.1; P = .008), and longer operating room time (4.8 vs 4.4 hours; P = .015). No differences were observed between the 2 groups in blood loss, time to discharge, or complication rate. Also, no significant differences were found in the surgical pathologic findings, including the organ-confined rate (62% vs 71%) and lymph node yield (19.5 vs 18.1).

CONCLUSIONS

Older patients do not appear to have any significant differences or compromises with regard to the perioperative and pathologic outcomes after robotic radical cystectomy. Thus, robotic radical cystectomy appears to be an appropriate surgical option for older patients.

摘要

目的

报告我们在机器人根治性膀胱切除术方面的成熟经验,涉及围手术期措施和病理结果,适用于老年患者人群。机器人根治性膀胱切除术最近已被描述用于膀胱癌,但在老年患者人群中的应用尚未评估,而膀胱癌和膀胱切除术通常就是这种情况。

方法

2006 年 1 月至 2009 年 10 月,我院共有 119 例患者因临床局限性膀胱癌接受机器人膀胱切除术和体外尿路转流术。由于本系列早期的患者选择,排除了前 20 例。连续病例的临床特征、手术结果和病理结果按年龄(<70 岁的年轻患者与≥70 岁的老年患者)进行分类。

结果

评估了 61 例年轻患者和 38 例老年患者(包括 7 例>80 岁)的结果。年轻患者的美国麻醉医师协会评分(2.6 对 3.0;P<0.001)、体质量指数(28.2 对 26.1;P=0.008)和手术时间(4.8 对 4.4 小时;P=0.015)均低于老年患者。两组间的出血量、出院时间或并发症发生率无差异。两组的手术病理发现也无显著差异,包括器官局限性率(62%对 71%)和淋巴结产量(19.5 对 18.1)。

结论

对于机器人根治性膀胱切除术,老年患者的围手术期和病理结果似乎没有任何显著差异或妥协。因此,机器人根治性膀胱切除术似乎是老年患者的一种合适的手术选择。

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