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黏膜下肌瘤新分类系统的可行性:一项多中心研究。

Feasibility of a new system of classification of submucous myomas: a multicenter study.

机构信息

Department of Gynecology and Obstetrics, Federal Fluminense University, Rio de Janeiro, Brazil.

出版信息

Fertil Steril. 2011 May;95(6):2073-7. doi: 10.1016/j.fertnstert.2011.01.147. Epub 2011 Feb 21.

Abstract

OBJECTIVE

To evaluate the performance of the STEPW (size, topography, extension, penetration, wall) classification system in predicting partial or complete fibroid removal on hysteroscopic myomectomy.

DESIGN

Multicenter, prospective study (Canadian Task Force classification II-2).

SETTING

Four hysteroscopy centers in Brazil, China, Italy, and the United States.

PATIENT(S): Four hundred forty-nine women who underwent hysteroscopic resection of 465 submucous fibroids.

INTERVENTION(S): Resection of the submucous fibroids (hysteroscopic myomectomy). Fibroids were scored according to the European Society for Gynaecological Endoscopy (ESGE) and STEPW classifications. The validation of the two classifications was assessed using sensitivity and specificity of each classification, with their best cutoff point. A test of equality of the two areas under the receiver operating characteristic curves was performed for correlated samples.

MAIN OUTCOME MEASURE(S): Correlation of ESGE and STEPW classifications with complete or incomplete removal of submucous fibroid.

RESULT(S): Removal of the myoma was complete in 432 (92.9%) of 465 myomectomies and incomplete in 33 (7.1%). All 320 fibroids (100%) with a score≤4 in the STEPW classification were completely removed, and 112 of 145 fibroids (77.2%) with a score>4 were removed. All 33 cases of incomplete hysteroscopic myomectomy (100%) had a STEPW score>4. Using the ESGE classification, 85 of 86 cases (98.9%) of type 0 fibroids, 278 of 298 (93.3%) of type 1, and 69 of 81 (85.2%) of type 2 were completely resected.

CONCLUSION(S): Classifying submucous fibroids using the STEPW classification permits greater correlation with complete or incomplete removal of the myoma by hysteroscopic myomectomy.

摘要

目的

评估 STEPW(大小、形态、扩展、穿透、壁)分类系统在预测宫腔镜子宫肌瘤切除术中部分或完全切除肌瘤的性能。

设计

多中心、前瞻性研究(加拿大任务组分类 II-2)。

地点

巴西、中国、意大利和美国的四个宫腔镜中心。

患者

449 名接受宫腔镜下切除 465 个黏膜下肌瘤的患者。

干预措施

切除黏膜下肌瘤(宫腔镜子宫肌瘤切除术)。根据欧洲妇科内镜学会(ESGE)和 STEPW 分类对肌瘤进行评分。使用两种分类的敏感性和特异性及其最佳截断点评估两种分类的验证。对相关样本进行了Receiver Operating Characteristic 曲线下面积相等性的检验。

主要观察指标

ESGE 和 STEPW 分类与黏膜下肌瘤完全或不完全切除的相关性。

结果

465 例子宫肌瘤切除术中有 432 例(92.9%)完全切除,33 例(7.1%)不完全切除。STE PW 分类评分≤4 的 320 个肌瘤(100%)均完全切除,评分>4 的 145 个肌瘤中有 112 个(77.2%)切除。33 例宫腔镜子宫肌瘤切除术不完全切除(100%)的 STEPW 评分均>4。使用 ESGE 分类,0 型 86 例(98.9%)、1 型 298 例(93.3%)和 2 型 81 例(85.2%)的肌瘤完全切除。

结论

使用 STEPW 分类对黏膜下肌瘤进行分类,可更好地预测宫腔镜子宫肌瘤切除术中肌瘤的完全或不完全切除。

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