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后颅窝手术后的小脑缄默症

Cerebellar mutism after posterior fossa surgery.

作者信息

Dietze D D, Mickle J P

机构信息

Department of Neurosurgery, University of Florida, Gainesville.

出版信息

Pediatr Neurosurg. 1990;16(1):25-31; discussion 31. doi: 10.1159/000120499.

Abstract

A large midline posterior fossa medulluloblastoma and a cerebellar arteriovenous malformation with associated clot were moved with postoperative mutism. Mutism was immediate and resolved into an ataxic dysarthria with residual mild dysarthria at 3 months. The literature is reviewed, and the clinicopathological and neurophysiological data of cerebellar function in speech are discussed. Acute injury to the midportion of the cerebellum with or without dentate nuclear involvement can cause a spectrum of speech disturbances. The more widespread the injury to the midportion of the cerebellum with dentate nuclei involvement the greater the risk of developing postoperative mutism.

摘要

一例大型后颅窝中线髓母细胞瘤及伴有血栓形成的小脑动静脉畸形术后出现缄默症。缄默症立即出现,并在3个月时演变为共济失调性构音障碍,残留轻度构音障碍。本文回顾了相关文献,并讨论了小脑功能在言语方面的临床病理及神经生理学数据。小脑中部急性损伤,无论是否累及齿状核,均可导致一系列言语障碍。小脑中部损伤范围越广且累及齿状核,术后发生缄默症的风险就越大。

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