Department of Epidemiology and Health Statistics, School of Public Health and Family Medicine, Capital Medical University, Beijing 100069, China.
Diabetes Res Clin Pract. 2011 May;92(2):265-71. doi: 10.1016/j.diabres.2011.01.021. Epub 2011 Feb 21.
We aimed to explore an optimal anthropometric indicator and optimal cut-off points for incident diabetes in Chinese adults.
61,703 subjects were followed for a median duration of 2 years. Body mass index, waist circumference, waist-to-hip ratio and waist-to-height ratio were collected base on a standard protocol. Receiver Operating Characteristic curve analyses were used to compare the predictive power of baseline BMI, WC, WHpR and WHtR for development of type 2 diabetes.
There were 2991 new cases of type 2 diabetes during follow-up. ROC curve analyses indicated that WHtR was the best predictor of type 2 diabetes for male (AUC = 0.633). For female, WHtR and WC had similar predictive ability (AUC = 0.701 and 0.695 respectively) and were superior to BMI. WHpR was the weakest predictor in both genders. The optimal WHtR cut-off values for incidence of type 2 diabetes were similar in both genders (0.53 vs. 0.52). BMI was higher in men (26 kg/m(2)) than women (24 kg/m(2)); and so did WC (91 cm in men vs. 85 cm in women).
WHtR, and to some degree WC, are the best predictors of type 2 diabetes, followed by BMI then WHpR which is the weakest predictor in the tested adults.
我们旨在探索中国人中用于预测糖尿病发病的最佳人体测量指标和最佳切点。
61703 名研究对象的中位随访时间为 2 年。采用标准方案收集体重指数、腰围、腰臀比和腰围身高比等人体测量学指标。受试者工作特征曲线分析用于比较基线 BMI、WC、WHpR 和 WHtR 对 2 型糖尿病发病的预测能力。
随访期间共发生 2991 例 2 型糖尿病新发病例。ROC 曲线分析表明，WHtR 是男性发生 2 型糖尿病的最佳预测指标（AUC=0.633）。对于女性，WHtR 和 WC 的预测能力相似（AUC 分别为 0.701 和 0.695），优于 BMI。WHpR 在两性中预测能力均较弱。WHtR 预测 2 型糖尿病发病的最佳切点值在两性中相似（男性为 0.53，女性为 0.52）。男性 BMI 高于女性（26kg/m2 比 24kg/m2）；WC 也是如此（男性 91cm，女性 85cm）。
WHtR 和在一定程度上 WC 是预测 2 型糖尿病的最佳指标，其次是 BMI，WHpR 是检测人群中预测能力最弱的指标。
