Department of Life Sciences, The University of Manchester, Manchester, United Kingdom.
Eye Contact Lens. 2011 Mar;37(2):99-105. doi: 10.1097/ICL.0b013e31820592b1.
This case study reports on how refraction, visual acuity, and ocular higher-order aberrations changed after rigid gas-permeable (RGP) lens wear was suspended by a patient with early pellucid marginal corneal degeneration (PMD) and by a patient with moderate keratoconus. Alterations in central corneal power and axes, central corneal thickness, and corneal topography were also explored.
Ocular aberrations and Scheimpflug photography were measured at 2 visits, 7 days apart, after the patients had removed their contact lenses. Subjective refraction and logarithm of the minimum angle of resolution visual acuities were also recorded at both visits.
In contrast to the keratoconic patient, the patient with early PMD showed changes in subjective refraction (approximately -1.75 diopter cylinder of astigmatism), front surface central powers (∼1.3 diopter [D] horizontally and 2 D vertically), and anterior surface topography (∼1.2 D) between visits. Both patients showed an increase in total higher-order root mean square (HORMS) aberrations after suspending lens wear (∼0.40 μm for the moderately keratoconic patient and 0.22 μm for the early PMD patient).
Changes in the optical and structural parameters of the cornea after suspending lens wear are likely to be dependent on a multitude of factors, such as the lens fitting and the biomechanical properties of the cornea. The findings of this report may be useful to practitioners when refracting or refitting existing RGP lens wearers with ectasia or to those involved in prescribing aberration-controlling contact lenses for conditions such as keratoconus and PMD.
本病例研究报告了早期板层状角膜营养不良(PMD)和中重度圆锥角膜患者停止硬性透气性角膜接触镜(RGP)佩戴后,其屈光度、视力和眼高阶像差的变化情况。还探讨了中央角膜曲率和轴位、中央角膜厚度和角膜地形图的变化。
在患者停戴接触镜后 7 天内的 2 次就诊时测量眼像差和 Scheimpflug 摄影。在这两次就诊时还记录了主观屈光度和最小分辨角视力的对数。
与圆锥角膜患者不同,早期 PMD 患者的主观屈光度(约-1.75 屈光度散光)、前表面中央曲率(水平约 1.3 屈光度[D]和垂直 2 D)和前表面地形图(约 1.2 D)在两次就诊之间发生了变化。两名患者在停戴镜片后总高阶均方根(HORMS)像差均增加(中重度圆锥角膜患者增加约 0.40 μm,早期 PMD 患者增加约 0.22 μm)。
停戴镜片后角膜光学和结构参数的变化可能取决于多种因素,如镜片适配和角膜的生物力学特性。本报告的发现可能对折射或重新配镜治疗角膜扩张或为圆锥角膜和 PMD 等疾病开具像差控制型隐形眼镜处方的医生有用。