Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Nat Chem Biol. 2011 Apr;7(4):197-9. doi: 10.1038/nchembio.532. Epub 2011 Feb 20.
It has been thought that phosphorus in biominerals made of amorphous calcium carbonate (ACC) might be related to ACC formation, but no such phosphorus-containing compounds have ever been identified. Crustaceans use ACC biominerals in exoskeleton and gastroliths so that they will have easy access to calcium carbonate inside the body before and after molting. We have identified phosphoenolpyruvate and 3-phosphoglycerate, intermediates of the glycolytic pathway, in exoskeleton and gastroliths and found them important for stabilizing ACC.
人们曾认为，无定形碳酸钙 (ACC) 生物矿物中的磷可能与 ACC 的形成有关，但从未鉴定出过此类含磷化合物。甲壳类动物在其外骨骼和胃石中使用 ACC 生物矿物，以便在蜕皮前后更容易获得体内的碳酸钙。我们已经在甲壳类动物的外骨骼和胃石中鉴定出了磷酸烯醇丙酮酸和 3-磷酸甘油酸，这两种物质是糖酵解途径的中间产物，并且发现它们对稳定 ACC 非常重要。
