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用于检测核苷酸、FAD 和 NADH 的荧光和比色化学传感器:2004-2010 年期间的重点研究。

Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010.

机构信息

Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.

出版信息

Chem Soc Rev. 2011 May;40(5):2222-35. doi: 10.1039/c0cs00169d. Epub 2011 Feb 18.

Abstract

Due to the biological importance of nucleotides and related species, such as XNP (where X = adenosine (A), uridine (U), cytidine (C), guanosine (G), and N = mono, di, tri), FAD and NADH, the development of optical probes for these molecules has recently been an active area of research. This tutorial review focuses on the contributions between 2004-2010 concerning the fluorescent or colorimetric sensors for these biomolecules, and is organized according to their target molecule's structural classification.

摘要

由于核苷酸和相关物质(如 XNP,其中 X 为腺嘌呤(A)、尿嘧啶(U)、胞嘧啶(C)、鸟嘌呤(G),N 为单、二、三)、黄素腺嘌呤二核苷酸(FAD)和烟酰胺腺嘌呤二核苷酸(NADH)的生物学重要性,这些分子的光学探针的开发最近成为一个活跃的研究领域。本综述教程重点介绍了 2004-2010 年期间有关这些生物分子的荧光或比色传感器的贡献,并根据其靶分子的结构分类进行了组织。

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