Dean G, Gray R
Medico-Social Research Board, Dublin, Ireland.
J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):899-902. doi: 10.1136/jnnp.53.10.899.
A cluster of multiple sclerosis (MS) patients has been reported in seven of 307 nurses in Key West, Florida. The MS death rates in British nurses and qualified medical practitioners were looked at and no increased mortality from multiple sclerosis was found. Neither was there an increase in mortality from motor neuron disease (amyotrophic lateral sclerosis), the control disease. Death rates from MS vary with social class, being highest in social class IIIN (skilled non-manual) and lowest in social class II (intermediate). These different rates may be due to MS causing health related occupational mobility. Allowance for the inter-class variability in MS death rates did not materially affect the conclusion that death from MS appears to be no more common than expected among nurses and doctors than in the general population. Possible explanations for the cluster of multiple sclerosis among nurses in Key West are discussed.
据报道，在佛罗里达州基韦斯特的307名护士中，有7人患多发性硬化症（MS）。研究了英国护士和合格医生中MS的死亡率，未发现多发性硬化症导致的死亡率增加。作为对照疾病的运动神经元病（肌萎缩侧索硬化症）的死亡率也没有增加。MS的死亡率因社会阶层而异，在社会阶层IIIN（熟练非体力劳动者）中最高，在社会阶层II（中级）中最低。这些不同的比率可能是由于MS导致与健康相关的职业流动。考虑到MS死亡率在不同阶层之间的差异，并未实质性影响以下结论：与普通人群相比，护士和医生中死于MS的情况似乎并不比预期更常见。文中讨论了基韦斯特护士中多发性硬化症聚集现象的可能解释。
