Li Shao-Yong, Xu Yao-Wei, Liu Jun-Min, Su Cheng-Yong
College of Pharmacy, Tianjin Medical University, Tianjin 300070, China; E-Mail:
Int J Mol Sci. 2011 Jan 17;12(1):429-55. doi: 10.3390/ijms12010429.
Inherently chiral calixarenes, whose chirality is based on the absence of a planar symmetry or an inversion center in the molecules as a whole through the asymmetric array of several achiral groups upon the three-dimensional calix-skeletons, are challenging and attractive chiral molecules, because of their potential in supramolecular chemistry. The synthesis and optical resolution of all varieties of inherently chiral calixarenes are systematically discussed and classified, and their applications in chiral recognition and asymmetric catalysis are thoroughly illustrated in this review.
固有手性杯芳烃是具有挑战性且极具吸引力的手性分子，其手性基于整个分子中不存在平面对称性或反演中心，这是通过三维杯状骨架上几个非手性基团的不对称排列实现的。由于其在超分子化学中的潜力，本文对各种固有手性杯芳烃的合成和光学拆分进行了系统的讨论和分类，并详细阐述了它们在手性识别和不对称催化中的应用。
