Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly.
作者信息
Liu Yan, Li Nan, Qi Yi-pin, Dai Lin, Bryan Thomas E, Mao Jing, Pashley David H, Tay Franklin R
机构信息
Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
出版信息
Adv Mater. 2011 Feb 22;23(8):975-80. doi: 10.1002/adma.201003882. Epub 2010 Dec 15.
Abstract
摘要
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PROTEIN TEMPLATES IN HARD TISSUE ENGINEERING.硬组织工程中的蛋白质模板
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Immobilization of a phosphonated analog of matrix phosphoproteins within cross-linked collagen as a templating mechanism for biomimetic mineralization.将基质磷蛋白的磷酸化类似物固定在交联胶原内作为仿生矿化的模板机制。
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Mineralisation of reconstituted collagen using polyvinylphosphonic acid/polyacrylic acid templating matrix protein analogues in the presence of calcium, phosphate and hydroxyl ions.使用聚（乙烯基膦酸）/聚（丙烯酸）模板蛋白类似物在钙离子、磷酸盐离子和羟基离子存在的情况下对重组胶原蛋白进行矿化。
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Amorphous calcium (ortho)phosphates.无定形的钙（正）磷酸盐。
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Mineralized biological materials: A perspective on interfaces and interphases designed over millions of years.矿化生物材料：关于历经数百万年形成的界面和中间相的见解。
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