National Key Laboratory of Nano/Micro Fabrication Technology, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, China.
Chem Asian J. 2011 May 2;6(5):1156-62. doi: 10.1002/asia.201000818. Epub 2011 Feb 21.
Bovine serum albumin (BSA)-conjugated M(x)Se(y) (M = Ag, Cd, Pb, Cu) nanomaterials with different shapes and sizes were synthesized in water at room temperature by a protein-directed, solution-phase, green synthetic method. The method features very low energy consumption and nontoxic reagents with high yields of concentrated nanoparticles. The obtained bioconjugated nanoparticles have good dispersibility, bioactivity, and biocompatibility. In addition, various functional groups of protein on the surface of the nanocrystals are suitable for further biological interactions or couplings, which is very important for further biological applications.
牛血清白蛋白（BSA）- 偶联的 M(x)Se(y)（M = Ag、Cd、Pb、Cu）纳米材料具有不同的形状和尺寸，通过蛋白质导向、溶液相、绿色合成方法在室温下于水中合成。该方法的特点是能量消耗非常低，使用的试剂无毒，并且可以高产浓缩纳米颗粒。所得到的生物偶联纳米颗粒具有良好的分散性、生物活性和生物相容性。此外，纳米晶体表面蛋白质的各种官能团适合进一步的生物相互作用或偶联，这对于进一步的生物应用非常重要。
