2009 年甲型 H1N1 流感在一所公立大学的传播——特拉华州，2009 年 4 月至 5 月。

Transmission of 2009 pandemic influenza A (H1N1) at a Public University--Delaware, April-May 2009.

机构信息

Epidemic Intelligence Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

Clin Infect Dis. 2011 Jan 1;52 Suppl 1:S131-7. doi: 10.1093/cid/ciq029.

Abstract

We investigated the first documented university outbreak of the 2009 pandemic influenza A(H1N1) to identify factors associated with disease transmission. An online student survey was administered to assess risk factors for influenza-like illness (ILI), defined as fever with cough or sore throat. Of 6049 survey respondents, 567 (9%) experienced ILI during 27 March to 9 May 2009. Studying with an ill contact (adjusted risk ratios [aRR], 1.29; 95% confidence intervals [CI], 1.01-1.65) and caring for an ill contact (aRR, 1.51; CI, 1.14-2.01) any time during 27 March to 9 May were predictors for ILI. Respondents reported that 680 (6%) of 11,411 housemates were ill; living with an ill housemate was a predictor for ILI (RR, 1.38; CI, 1.04-1.83). Close contact or prolonged exposures to ill persons were likely associated with experiencing ILI. Self-protective measures should be promoted in university populations to mitigate transmission.

摘要

我们调查了 2009 年大流行性流感 A(H1N1)的首例有记录的大学暴发，以确定与疾病传播相关的因素。我们对学生进行了在线调查，以评估流感样疾病（ILI）的危险因素，ILI 的定义为发热伴咳嗽或咽痛。在 2009 年 3 月 27 日至 5 月 9 日期间，6049 名调查对象中有 567 人（9%）患有 ILI。任何时候与患病接触者一起学习（调整后的风险比[aRR]，1.29；95%置信区间[CI]，1.01-1.65）和照顾患病接触者（aRR，1.51；CI，1.14-2.01）均是 ILI 的预测因素。受访者报告称，11411 名室友中有 680 人（6%）患病；与患病室友同住是 ILI 的预测因素（RR，1.38；CI，1.04-1.83）。与患病者的密切接触或长时间接触可能与经历 ILI 有关。应在大学人群中推广自我保护措施以减轻传播。