Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
作者信息
Ishikawa Minoru, Hashimoto Yuichi
机构信息
Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.
出版信息
J Med Chem. 2011 Mar 24;54(6):1539-54. doi: 10.1021/jm101356p. Epub 2011 Feb 23.
PMID:21344906
Abstract
摘要
Zotero 插件