Division of Gastroenterology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, People’s Republic of China.
J Clin Microbiol. 2011 May;49(5):1987-9. doi: 10.1128/JCM.02630-10. Epub 2011 Feb 23.
Based on 16S rRNA gene PCR, no significant difference was observed in rates of detection of Helicobacter species in intestinal biopsy specimens from 160 Chinese inflammatory bowel disease (IBD) patients (10%) and 80 controls (6.3%). By using a [(13)C]urea breath test, the H. pylori infection rate in 208 Chinese IBD patients (19.7%) was found to be significantly lower than that in 416 controls (48.8%).
基于 16S rRNA 基因 PCR,在对 160 例中国炎症性肠病(IBD)患者(10%)和 80 例对照者(6.3%)的肠活检标本中检测幽门螺旋杆菌(Helicobacter)种的检出率没有显著差异。通过使用 [(13)C]尿素呼气试验,发现 208 例中国 IBD 患者(19.7%)的 H. pylori 感染率显著低于 416 例对照者(48.8%)。