Mdivani M, Betaneli M, Margvelashvili V, Kharabadze M
P. Shotadze Tbilisi Medical Academy, Tbilisi, Georgia.
Georgian Med News. 2011 Jan(190):24-7.
Pregnancy gingivitis is developed in 30-75% of cases and it is a result of complicated hormonal and immunological changes in the organism. 100 pregnant women with various degree of severity of gingivitis have been observed. Acute generalized gingivitis, gingival edema with bleeding, hyperplasia, have been observed in all patients, while in bad cases - with ulcers' formation at gingival. Decrease of hemoreological index of gingival tissue (down to 0,15-0,19 Ohm) have been mentioned, too. Complete clinical and laboratory studies, as well as screening of obtained data have been carried out before the treatment, in its process and after the course. Pregnant women have been under the supervision, to whom according to various indications (rhesus-imcompatibility, antiphospholipidic syndrome, early interruption of pregnancy with disorder of the system of hemostasis basically towards hypercoagulation) has been carried out curative discrete plasmapheresis. All pregnant women have been diagnosed by the gingivitis of varying severity. After completion of curative course of plasmapheresis has been carried out evaluation of patients' condition. It has been reached improvement of subjective and objective data, regulation of hemoreological data in gingival tissue (0,21-0,23 Ohm). Respectively, the period of recurrence-free course of disease have been increased and the quality of patients' life have been improved.
30%至75%的病例会发生妊娠牙龈炎，这是机体复杂的激素和免疫变化的结果。观察了100名患有不同程度牙龈炎的孕妇。所有患者均出现急性全身性牙龈炎、牙龈水肿伴出血、增生，而病情严重者牙龈会形成溃疡。还提到牙龈组织血液流变学指标下降（降至0.15 - 0.19欧姆）。在治疗前、治疗过程中和疗程结束后都进行了全面的临床和实验室研究以及对所获数据的筛查。对孕妇进行了监测，根据各种指征（恒河猴血型不相容、抗磷脂综合征、既往有止血系统紊乱基本倾向于高凝状态的早期妊娠中断史）对她们进行了治疗性离散血浆置换。所有孕妇均被诊断为患有不同严重程度的牙龈炎。在完成血浆置换治疗疗程后，对患者的病情进行了评估。主观和客观数据均有改善，牙龈组织血液流变学数据得到调节（0.21 - 0.23欧姆）。相应地，疾病无复发期延长，患者生活质量得到改善。
