Sudan Atomic Energy Commission, Algamaa Street, PO Box 3001, Khartoum, Sudan.
Bull World Health Organ. 2011 Feb 1;89(2):121-6. doi: 10.2471/BLT.09.075002. Epub 2010 Oct 22.
To describe the status of iodine deficiency disorders (IDDs) in the Sudan more than 25 years after the initiation of IDD control programmes and to explore the causes of endemic goitre in the country.
Testing for IDDs was carried out in 6083 schoolchildren 6 to 12 years of age from the capital cities of nine states in different areas of the country using the three indicators recommended by the World Health Organization: the prevalence of goitre, laboratory measurements of urinary iodine concentration in casual urine samples and serum thyroglobulin (Tg) levels. Serum levels of thyroxine (T4), triiodothyronine (T3) and thyroid-stimulating hormone (TSH), as well as urinary secretion of thiocyanate, which can affect the transport of iodine into thyrocytes, were also measured.
The prevalence of goitre in the different samples ranged from 12.2% to 77.7% and was 38.8% overall. The overall median urinary iodine concentration was 6.55 μg/dl, with the lowest median value having been found in Kosti city (2.7 μg/dl), situated in the centre of the country, and the highest (46.4 μg/dl) in Port Sudan, on the Red Sea coast. The highest mean serum Tg level (66.98 ng/ml) was found in Kosti city, which also had the highest prevalence of goitre.
IDDs still constitute a public health problem throughout urban areas in the Sudan and iodine deficiency appears to be the main etiological factor involved.
描述在启动碘缺乏病（IDD）控制项目 25 年多后苏丹碘缺乏症的现状，并探讨该国地方性甲状腺肿的原因。
在该国不同地区的九个州的首府，对 6083 名 6 至 12 岁的在校儿童使用世界卫生组织推荐的三个指标进行 IDD 检测：甲状腺肿患病率、随意尿液样本中尿碘浓度的实验室测量值和血清甲状腺球蛋白（Tg）水平。还测量了血清甲状腺素（T4）、三碘甲状腺原氨酸（T3）和促甲状腺激素（TSH）水平以及尿液中硫氰酸盐的排泄量，后者会影响碘向甲状腺细胞的转运。
不同样本的甲状腺肿患病率在 12.2%至 77.7%之间，总体患病率为 38.8%。总体中位数尿碘浓度为 6.55μg/dl，其中中部城市科斯蒂（2.7μg/dl）的中位数最低，红海沿岸的苏丹港（46.4μg/dl）最高。科斯蒂市的血清 Tg 水平最高（66.98ng/ml），甲状腺肿患病率也最高。
碘缺乏症仍然是苏丹城市地区的一个公共卫生问题，碘缺乏似乎是主要的病因因素。
