Sudan Atomic Energy Commission, Khartoum, Sudan.
Public Health Nutr. 2013 Sep;16(9):1586-92. doi: 10.1017/S1368980012004685. Epub 2012 Nov 16.
To study the associations between intakes of iodine and water chemicals and the thyroid gland status of schoolchildren living in the coastal city of Port Sudan.
In our previous nationwide study on goitre, it was observed that the prevalence of goitre was high in Port Sudan city despite high urinary iodine excretion. A cross-sectional study including schoolchildren aged 6–12 years was designed. Measurements determined the prevalence of goitre, urinary iodine concentration and thiocyanate secretion in casual urine samples, serum levels of thyroxine, triiodothyronine, thyroid-stimulating hormone and thyroglobulin, as well as the levels of Cl⁻, F⁻, Ca²⁺, Mg²⁺ and total hardness of drinking water.
Schoolchildren (n 654) aged 6–12 years.
Port Sudan city is located at the western bank of the Red Sea. The city is surrounded by a mountainous area known as the Red Sea Hills. It is the main sea port in the Sudan, inhabited by ethnically and socio-economically heterogeneous populations.
The prevalence of goitre in Port Sudan was 34.86% while the median urinary iodine concentration was 46,4μg/dl. Out of thirty-one pupils from Port Sudan, twenty-four (77.42 %) were found to have urinary iodine concentration greater than 30μg/dl and twelve (38.71 %) had different degrees of biochemical hypothyroidism. Excessive concentrations of Cl⁻, Ca²⁺, Mg²⁺ and water hardness (369.2, 116.48, 60.21 and 539.0mg/l, respectively) were detected in drinking water samples collected from Port Sudan that exceeded levels permitted by the WHO.
The coastal city of Port Sudan is a goitre-endemic area. In contrast to other Sudanese cities in which endemic goitre is related to iodine deficiency, goitre in Port Sudan is associated with iodine excess. Water chemicals seemed to have no effects on thyroid status.
研究居住在苏丹沿海城市苏丹港的儿童碘和水化学物质摄入量与甲状腺状况之间的关系。
在我们之前关于甲状腺肿的全国性研究中，观察到尽管尿碘排泄量高，但苏丹港城市的甲状腺肿患病率很高。设计了一项包括 6-12 岁学龄儿童的横断面研究。测量确定了甲状腺肿的患病率、随意尿样中的尿碘浓度和硫氰酸盐分泌、血清甲状腺素、三碘甲状腺原氨酸、促甲状腺激素和甲状腺球蛋白水平以及饮用水中 Cl⁻、F⁻、Ca²⁺、Mg²⁺ 和总硬度水平。
6-12 岁学龄儿童（n=654）。
苏丹港城市位于红海西岸。该市被称为红海山的山区所环绕。它是苏丹的主要海港，居住着种族和社会经济背景各异的人群。
苏丹港的甲状腺肿患病率为 34.86%，而中位数尿碘浓度为 46.4μg/dl。在来自苏丹港的三十一名学生中，有二十四名（77.42%）尿碘浓度大于 30μg/dl，有十二名（38.71%）有不同程度的生化甲状腺功能减退症。从苏丹港采集的饮用水样本中检测到 Cl⁻、Ca²⁺、Mg²⁺ 和水硬度（分别为 369.2、116.48、60.21 和 539.0mg/l）的浓度过高，超过了世界卫生组织允许的水平。
苏丹沿海城市苏丹港是甲状腺肿流行地区。与其他苏丹城市的碘缺乏相关的地方性甲状腺肿不同，苏丹港的甲状腺肿与碘过量有关。水化学物质似乎对甲状腺状态没有影响。
