用于表示门诊处方的RxNorm评估。
Evaluation of RxNorm for Representing Ambulatory Prescriptions.
作者信息
O'Neill Sean M, Bell Douglas S
机构信息
RAND Corporation, Santa Monica, CA;
出版信息
AMIA Annu Symp Proc. 2010 Nov 13;2010:562-6.
OBJECTIVE
We evaluated the RxNorm standardized drug nomenclature for representing ambulatory e-prescriptions.
METHODS
Using a sample of 19743 primary care e-prescriptions, we estimated the coverage rate of RxNorm for representing clinical drugs, measured the 6-month replacement rate for RxNorm concepts, assessed the consistency of two independent concept mappings, and investigated inconsistent mappings.
RESULTS
RxNorm contained concepts for nearly all prescriptions in the sample (99.995%). Of 1419 concepts used, 8.1% were replaced between April and October 2009. Independent mappings produced different concepts for 676 e-prescriptions (3.4%), but most differences would have low clinical significance. Most mismatches were related to the use of extended-release form concepts with no duration specified, inhalers vs. their contents, and clinically inert salts.
CONCLUSIONS
RxNorm provides concepts covering nearly all ambulatory e-prescriptions in this setting. Independent mappings were relatively consistent. Improvements could be made by enabling selection of the most-specific concepts when broader prescribable concepts exist.
目的
我们评估了用于表示门诊电子处方的RxNorm标准化药物命名法。
方法
我们以19743份初级保健电子处方为样本，估计了RxNorm对临床药物的覆盖率，测量了RxNorm概念的6个月替换率，评估了两种独立概念映射的一致性，并调查了不一致的映射。
结果
RxNorm包含了样本中几乎所有处方的概念（99.995%）。在使用的1419个概念中，2009年4月至10月期间有8.1%被替换。独立映射对676份电子处方（3.4%）产生了不同的概念，但大多数差异的临床意义较低。大多数不匹配与未指定持续时间的缓释剂型概念的使用、吸入器与其内容物以及临床惰性盐有关。
结论
在这种情况下，RxNorm提供了涵盖几乎所有门诊电子处方的概念。独立映射相对一致。当存在更宽泛的可处方概念时，通过启用选择最具体的概念可以进行改进。
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