Minces L R, Bhama J K, Abdel-Massih R, Kwak E J, Haider S S, Nguyen M H, Toyoda Y, Silveira F P
Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Transpl Infect Dis. 2011 Oct;13(5):485-8. doi: 10.1111/j.1399-3062.2011.00615.x. Epub 2011 Feb 23.
The outcome of patients with aspergilloma undergoing lung transplantation is not completely known, but anecdotal reports of poor outcome after transplant have discouraged this practice. We present a 45-year-old female with pulmonary sarcoidosis complicated by bilateral pulmonary and sinus aspergillomas who underwent successful double lung transplantation. Patients with aspergillomas can receive lung transplantation, provided that there is sufficient technical expertise to explant the infected lungs with minimal chance of chest wall contamination, and aggressive antifungal therapy is used post transplantation.
肺移植治疗曲菌球患者的预后尚不完全清楚,但移植后预后不佳的个案报道使这种治疗方法受到了阻碍。我们报告一例45岁女性,患有结节病合并双侧肺及鼻窦曲菌球,成功接受了双肺移植。患有曲菌球的患者可以接受肺移植,前提是有足够的技术专长以在最小化胸壁污染风险的情况下切除受感染的肺,并且在移植后采用积极的抗真菌治疗。