Diagnostic Imaging and Neurosciences & Mental Health, Research Institute, Hospital for Sick Children, University of Toronto, ON, Canada.
Brain Topogr. 2011 Jun;24(2):149-63. doi: 10.1007/s10548-011-0171-4. Epub 2011 Feb 25.
Neuroimaging evidence suggests that dynamic facial expressions elicit greater activity than static face stimuli in brain structures associated with social cognition, interpreted as greater ecological validity. However, a quantitative meta-analysis of brain activity associated with dynamic facial expressions is lacking. The current study investigated, using three fMRI experiments, activity elicited by (a) dynamic and static happy faces, (b) dynamic and static happy and angry faces, and (c) dynamic faces and dynamic flowers. In addition, using activation likelihood estimate (ALE) meta-analysis, we determined areas concordant across published studies that (a) used dynamic faces and (b) specifically compared dynamic and static emotional faces. The middle temporal gyri (Experiment 1) and superior temporal sulci (STS; Experiment 1 and 2) were more active for dynamic than static faces. In contrasts with the baseline the amygdalae were more active for dynamic faces (Experiment 1 and 2) and the fusiform gyri were active for all conditions (all Experiments). The ALE meta-analyses revealed concordant activation in all of these regions as well as in areas associated with cognitive manipulations (inferior frontal gyri). Converging data from the experiments and the meta-analyses suggest that dynamic facial stimuli elicit increased activity in regions associated with interpretation of social signals and emotional processing.
神经影像学证据表明，与社会认知相关的大脑结构中，动态面部表情比静态面部刺激引起更大的活动，被解释为更具生态有效性。然而，缺乏与动态面部表情相关的大脑活动的定量荟萃分析。本研究使用三个 fMRI 实验，研究了（a）动态和静态快乐面孔、（b）动态和静态快乐和愤怒面孔以及（c）动态面孔和动态花朵引起的活动。此外，我们使用激活似然估计 (ALE) 荟萃分析，确定了在（a）使用动态面孔和（b）专门比较动态和静态情绪面孔的已发表研究中一致的区域。颞中回（实验 1）和颞上回（STS；实验 1 和 2）对动态面孔的活动比静态面孔更活跃。与基线相比，杏仁核在动态面孔（实验 1 和 2）中更活跃，梭状回在所有条件下（所有实验）都活跃。ALE 荟萃分析显示，所有这些区域以及与认知操作相关的区域（额下回）都有一致的激活。实验和荟萃分析的汇聚数据表明，动态面部刺激会引起与社会信号解释和情绪处理相关的区域活动增加。
