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机器人增强全内镜冠状动脉旁路移植术中转开胸的预测因素、原因和后果。

Predictors, causes, and consequences of conversions in robotically enhanced totally endoscopic coronary artery bypass graft surgery.

机构信息

University Clinic of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria.

出版信息

Ann Thorac Surg. 2011 Mar;91(3):647-53. doi: 10.1016/j.athoracsur.2010.10.072.

Abstract

BACKGROUND

Totally endoscopic coronary artery bypass graft surgery (TECAB), using the da Vinci telemanipulator, has become a reproducible operation at dedicated centers. As in every endoscopic operation, conversion is an important and probably inevitable issue.

METHODS

We performed robotic TECAB in 326 patients (age, 60 years; range, 31 to 90 years); 242 were single-vessel and 84 were multivessel TECAB.

RESULTS

Forty-six of 326 patients (14%) were converted to a larger incision (minithoracotomy, n = 5; sternotomy, n = 41). Left internal mammary artery injury (n = 7), epicardial injury (n = 4), balloon endoocclusion problems (n = 7), and anastomotic problems (n = 18) were common reasons for conversions. Conversion rate was significantly less for single-vessel versus multivessel TECABs (10% versus 25%; p = 0.001). Non-learning-curve case (7% versus 21%; p < 0.001) and transthoracic assistance (11% versus 22%; p = 0.018) were associated with lower conversion rates. In multivariate analysis, learning-curve case was the only independent predictor of conversion (p = 0.005). Conversion translated into increased packed red blood cell transfusion in the operating room (3 versus 0 units; p < 0.001), longer ventilation time (14 versus 8 hours; p < 0.001), and intensive care unit stay (45 versus 20 hours; p = 0.001). Hospital mortality was 0.6% in this series, with 1 patient in the conversion group (2.2%) and 1 patient in the nonconverted group (0.4%; not significant). Five-year survival was 98% in nonconverted patients and 88% in converted patients (p = 0.018). There was no difference in freedom from angina or freedom from major adverse cardiac and cerebral events.

CONCLUSIONS

Conversion in TECAB is primarily learning curve-dependent and associated with increased morbidity, but does not significantly affect hospital mortality. Both nonconverted and converted patients show good long-term survival, which is comparable to patients undergoing open sternotomy coronary artery bypass grafting. Long-term freedom from angina or freedom from major adverse cardiac and cerebral events is not influenced by conversion.

摘要

背景

使用达芬奇远程操纵器的全内窥镜冠状动脉旁路移植术(TECAB)已成为专门中心可重复进行的手术。与所有内窥镜手术一样,中转开胸是一个重要且可能不可避免的问题。

方法

我们对 326 例患者(年龄 60 岁;范围 31 至 90 岁)进行了机器人 TECAB;242 例为单支血管 TECAB,84 例为多支血管 TECAB。

结果

326 例患者中有 46 例(14%)中转开胸(小切口开胸 5 例;胸骨切开术 41 例)。左内乳动脉损伤(7 例)、心外膜损伤(4 例)、球囊堵塞问题(7 例)和吻合口问题(18 例)是中转的常见原因。单支血管 TECAB 与多支血管 TECAB 的中转率有显著差异(10%比 25%;p = 0.001)。非学习曲线病例(7%比 21%;p < 0.001)和经胸辅助(11%比 22%;p = 0.018)与较低的中转率相关。多变量分析显示,学习曲线病例是中转的唯一独立预测因素(p = 0.005)。中转导致手术室中红细胞输注增加(3 单位比 0 单位;p < 0.001)、通气时间延长(14 小时比 8 小时;p < 0.001)和重症监护病房停留时间延长(45 小时比 20 小时;p = 0.001)。本系列患者的院内死亡率为 0.6%,中转组 1 例(2.2%),未中转组 1 例(0.4%;无显著差异)。未中转患者的 5 年生存率为 98%,中转患者为 88%(p = 0.018)。两组间心绞痛无复发率或主要不良心脏和脑血管事件无复发率无差异。

结论

TECAB 中转主要取决于学习曲线,与发病率增加有关,但不会显著影响院内死亡率。未中转和中转的患者均显示出良好的长期生存率,与接受胸骨切开术冠状动脉旁路移植术的患者相当。长期无心绞痛或无主要不良心脏和脑血管事件不受中转影响。

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