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机器人全内镜冠状动脉旁路移植术后影响住院时间的因素。

Factors influencing hospital length of stay after robotic totally endoscopic coronary artery bypass grafting.

机构信息

Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

出版信息

Ann Thorac Surg. 2013 Mar;95(3):813-8. doi: 10.1016/j.athoracsur.2012.10.087. Epub 2013 Jan 24.

Abstract

BACKGROUND

Robotic totally endoscopic coronary artery bypass grafting (TECAB) is an evolving minimally invasive technology with the potential to reduce hospital length of stay (LOS). Little is known about the factors that influence LOS after this procedure. The aim of this study is to define the preoperative, intraoperative, and postoperative variables that predict LOS after TECAB.

METHODS

From 2001 to 2011, 541 patients, aged 60 years (range, 26 to 90 years), 394 (72.8%) male, 147 (27.1%) female, underwent TECAB using the daVinci telemanipulation system at one European and one American institution. Three hundred forty-six (63.9%) single-, 171 (31.6%) double-, 23 (4.2%) triple-, and 1 (0.2%) quadruple-vessel TECABs were carried out with an overall LOS of 6 days (range, 2 to 54 days) and 30-day mortality of 0.9% (5 of 541); 44.5% of patients (241 of 541) were hybrid intent-to-treat candidates.

RESULTS

The following variables showed significant positive correlation with LOS: age, r = 0.188 (p < 0.001); Society of Thoracic Surgeons risk score, r = 0.263 (p < 0.001); EuroSCORE, r = 0.191 (p < 0.001); creatinine, r = 0.135 (p = 0.002); and operative time, r = 0.216 (p < 0.001). Other factors that had significant influence on LOS were hemodialysis (p = 0.037), cerebrovascular disease (p = 0.002), learning curve case (p < 0.001), intraoperative surgical problem (p < 0.001), conversion or on-table revision (p < 0.001), revision for bleeding (p < 0.001), postoperative stroke (p < 0.001), intraaortic balloon pump (p < 0.001), hemodialysis (p < 0.001), and atrial fibrillation (p < 0.001). By multivariate analysis, learning curve case, conversion or on-table revision, and revision for bleeding were independent predictors for prolonged LOS (defined as LOS > 6 days).

CONCLUSIONS

Multiple variables affect LOS after TECAB. Older patients, patients on hemodialysis, patients with cerebrovascular disease, and those with higher general risk scores should expect prolonged LOS. Intraoperative surgical difficulties and conversion to open coronary artery bypass grafting also lead to extended LOS. Postoperative events that are known to prolong LOS in open coronary artery bypass grafting also prolong LOS after TECAB.

摘要

背景

机器人全内镜冠状动脉旁路移植术(TECAB)是一种微创技术,具有缩短住院时间(LOS)的潜力。目前,人们对影响这种手术后 LOS 的因素知之甚少。本研究旨在明确预测 TECAB 术后 LOS 的术前、术中及术后变量。

方法

2001 年至 2011 年,在一家欧洲机构和一家美国机构,使用达芬奇远程操作系统对 541 名年龄 60 岁(26-90 岁)的患者进行了 TECAB 手术,其中 394 名(72.8%)为男性,147 名(27.1%)为女性。共进行了 346 例(63.9%)单支、171 例(31.6%)双支、23 例(4.2%)三支和 1 例(0.2%)四支血管 TECAB,LOS 为 6 天(2-54 天),30 天死亡率为 0.9%(5/541);44.5%的患者(241/541)为杂交治疗意向患者。

结果

以下变量与 LOS 呈显著正相关:年龄,r = 0.188(p < 0.001);胸外科医师协会风险评分,r = 0.263(p < 0.001);欧洲心脏手术风险评估系统,r = 0.191(p < 0.001);肌酐,r = 0.135(p = 0.002);手术时间,r = 0.216(p < 0.001)。对 LOS 有显著影响的其他因素包括:血液透析(p = 0.037)、脑血管疾病(p = 0.002)、学习曲线病例(p < 0.001)、术中手术问题(p < 0.001)、转为开胸冠状动脉旁路移植术或在台上修改(p < 0.001)、因出血修改(p < 0.001)、术后中风(p < 0.001)、主动脉内球囊反搏(p < 0.001)、血液透析(p < 0.001)和心房颤动(p < 0.001)。多变量分析显示,学习曲线病例、转为开胸冠状动脉旁路移植术或在台上修改以及因出血修改是 LOS 延长的独立预测因素(定义为 LOS > 6 天)。

结论

多种因素影响 TECAB 术后 LOS。年龄较大、血液透析、脑血管疾病和一般风险评分较高的患者预计 LOS 较长。术中手术困难和转为开胸冠状动脉旁路移植术也会导致 LOS 延长。已知会延长开放冠状动脉旁路移植术 LOS 的术后事件也会延长 TECAB 术后 LOS。

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