Department of Psychiatry, Medical School, University of Campinas (UNICAMP), São Paulo, Brazil.
Schizophr Res. 2011 May;128(1-3):124-6. doi: 10.1016/j.schres.2011.01.023. Epub 2011 Feb 24.
Patients with deficit schizophrenia have worse cognition and poorer social functioning compared to the nondeficit ones. Insight is another domain in which these two groups might differ, but data on insight impairment in deficit versus nondeficit schizophrenia are still scarce. We compared 29 patients with deficit schizophrenia to 44 nondeficit patients and found a tendency to poorer insight in the deficit group. However such tendency disappeared when analysis was controlled for cognition, a domain in which both groups differed significantly. This finding reinforces the pressing need for simultaneous assessment of the several dimensions or domains of schizophrenic psychopathology.
与非缺陷型精神分裂症患者相比，缺陷型精神分裂症患者的认知功能和社会功能更差。自知力是这两组患者可能存在差异的另一个领域，但关于缺陷型和非缺陷型精神分裂症患者自知力损害的数据仍然很少。我们比较了 29 例缺陷型精神分裂症患者和 44 例非缺陷型精神分裂症患者，发现缺陷型组的自知力有下降的趋势。然而，当分析控制在认知领域时，这种趋势就消失了，而在认知领域，两组患者有显著差异。这一发现强调了同时评估精神分裂症病理的几个维度或领域的迫切需要。
