Department of Psychiatry, Medical School, University of Campinas (Unicamp), SP, Brazil; LINEU, Integrated Laboratories of Neuropsychology, Institute of Psychiatry, Medical School, University of São Paulo (USP), SP, Brazil.
Department of Psychiatry, Medical School, University of Campinas (Unicamp), SP, Brazil.
Schizophr Res. 2013 Jun;147(1):91-94. doi: 10.1016/j.schres.2013.02.041. Epub 2013 Mar 25.
Previous studies have shown correlations between poor insight and neurocognitive impairment in schizophrenia. Deficit schizophrenia has been associated with worse cognitive functioning and poorer insight. This study aimed at investigating the relationship between insight dimensions (measured by Schedule for the Assessment of Insight-Expanded Version and its factors) and specific neurocognitive functions (assessed through a battery of neuropsychological tests) considering separately patients with deficit (n=29) and nondeficit schizophrenia (n=44), categorized according to the Schedule for the Deficit Syndrome. We found that working memory correlated positively and significantly with awareness of mental illness in both groups. In nondeficit group, awareness of mental illness correlated additionally with verbal fluency and attention. If confirmed by further studies, these results may have important consequences, such as the need of tailoring differently cognitive rehabilitation for each group.
先前的研究表明，精神分裂症患者的洞察力差与神经认知功能损害之间存在相关性。缺陷型精神分裂症与认知功能更差和洞察力更差有关。本研究旨在根据缺陷综合征量表分别对缺陷型（n=29）和非缺陷型精神分裂症患者（n=44）进行分类，通过一系列神经心理测试来评估特定的神经认知功能，以探讨洞察力维度（用扩展版精神检查量表及其因子来衡量）与特定神经认知功能之间的关系。我们发现，工作记忆与两组的精神病意识均呈正相关且显著相关。在非缺陷组中，精神病意识还与言语流畅性和注意力相关。如果进一步的研究得到证实，这些结果可能具有重要意义，例如需要为每个组量身定制不同的认知康复治疗。
