Ekinci Okan, Albayrak Yakup, Ekinci Asli
Department of Psychiatry, Yozgat State Hospital, Yozgat, Turkey.
J Nerv Ment Dis. 2012 Jan;200(1):44-50. doi: 10.1097/NMD.0b013e31823e66af.
Patients with deficit schizophrenia have worse cognition and poorer social functioning compared with those with nondeficit schizophrenia. Insight is another domain in which these two groups might differ. However, there is no literature data specifically on cognitive insight impairment in deficit versus nondeficit schizophrenia. We compared 40 patients with deficit schizophrenia with 81 nondeficit patients and found that schizophrenic patients with deficit syndrome were more self-reflective and have higher self-reflectiveness-self-certainty index scores than did those without deficit syndrome. These differences remained significant when analysis was controlled for sex, age, education, and depression severity. On the other hand, there was no significant difference in self-certainty scores between two groups. In addition, we found significant relationships between cognitive insight and specific psychotic symptoms. A better understanding of the cognitive component of insight in schizophrenia with deficit syndrome may help us to understand the true relationship between insight and negative symptoms and contribute to the development of more efficient cognitive strategies, thus improving patients' outcome in a severely disabled psychiatric patient group.
与非缺陷型精神分裂症患者相比，缺陷型精神分裂症患者的认知功能更差，社会功能也更差。自知力是这两组患者可能存在差异的另一个领域。然而，目前尚无专门针对缺陷型与非缺陷型精神分裂症患者认知自知力损害的文献数据。我们将40例缺陷型精神分裂症患者与81例非缺陷型患者进行了比较，发现有缺陷综合征的精神分裂症患者比没有缺陷综合征的患者更善于自我反思，且自我反思-自我确定指数得分更高。在对性别、年龄、教育程度和抑郁严重程度进行分析控制后，这些差异仍然显著。另一方面，两组患者的自我确定得分没有显著差异。此外，我们发现认知自知力与特定的精神病性症状之间存在显著关系。更好地理解缺陷综合征精神分裂症患者自知力的认知成分，可能有助于我们理解自知力与阴性症状之间的真实关系，并有助于开发更有效的认知策略，从而改善重度残疾精神病患者群体的治疗效果。
