Laboratory for Molecular Diagnostics, CHAMBON Laboratories, Prague, Czech Republic.
Diagn Microbiol Infect Dis. 2011 Mar;69(3):266-70. doi: 10.1016/j.diagmicrobio.2010.10.004.
Hematooncologic patients often host rare or fastidious pathogens. Using 16S rDNA sequencing and transmission electron microscopy, we have identified 2 lymphoma patients infected with Candidatus Neoehrlichia mikurensis. In both individuals, the clinical presentation suggested ehrlichiosis-like syndrome. We believe that molecular techniques open new vistas in the field of pathogen detection.
血液肿瘤患者常携带罕见或难以培养的病原体。我们通过 16S rDNA 测序和透射电子显微镜，鉴定出 2 例淋巴瘤患者感染了候选新立克次体。在这 2 例患者中，临床表现提示为类埃立克体病综合征。我们认为分子技术为病原体检测开辟了新的前景。
