The Department of Special Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, No. 225, Changhai Road, Shanghai 200438, China.
Eur J Radiol. 2012 Apr;81(4):623-9. doi: 10.1016/j.ejrad.2011.01.079. Epub 2011 Feb 26.
To determine characteristic magnetic resonance (MR) imaging features of solitary necrotic nodule of the liver.
MR images features of thirty-two patients (17 men, 15 women; mean age, 43 years; range, 24-76 years) with pathologically proved solitary necrotic nodule of the liver were retrospectively analyzed for number, size, signal intensity features and enhancement patterns.
A total of 33 lesions were identified. The mean diameter was 2.3cm (range 1.0-4.5cm). Thirty lesions (90.9%) were 1.0-3.0cm in diameter and only 3 lesions (9.1%) were larger than 3.0cm. On T1-weighted images, solitary necrotic nodule of the liver appeared hypointense in 31 lesions (93.9%) and isointense in 2 lesions (6.1%). On T2-weighted images, 12 (36.4%) lesions were hyperintense, 15 (45.4%) were isointense or invisible and 6 (18.2%) were hypointense. After injection of gadopentetate dimeglumine, all lesions were hypointense and none of them showed enhancement.
Solitary necrotic nodule of the liver is usually small with the size not exceed 3.0cm in diameter. Absence of enhancement on all dynamic phase after gadopentetate dimeglumine administration may be most characteristic feature of solitary necrotic nodule of the liver on MR images, which may help discriminate this entity from metastatic liver tumors and intrahepatic cholangiocarcinoma.
确定肝脏单发坏死性结节的磁共振成像(MR)特征。
回顾性分析 32 例经病理证实的肝脏单发坏死性结节患者的 MR 图像特征,包括数量、大小、信号强度特征和增强模式。
共发现 33 个病灶,平均直径为 2.3cm(范围 1.0-4.5cm)。30 个病灶(90.9%)直径为 1.0-3.0cm,仅 3 个病灶(9.1%)直径大于 3.0cm。T1 加权图像上,肝脏单发坏死性结节 31 个(93.9%)呈低信号,2 个(6.1%)呈等信号。T2 加权图像上,12 个(36.4%)病灶呈高信号,15 个(45.4%)呈等信号或不可见,6 个(18.2%)呈低信号。钆喷替酸葡甲胺注射后,所有病灶均呈低信号,均未见强化。
肝脏单发坏死性结节通常较小,直径不超过 3.0cm。钆喷替酸葡甲胺增强后各期均无强化可能是肝脏单发坏死性结节的最特征性 MR 表现,有助于与转移性肝肿瘤和肝内胆管细胞癌相鉴别。