Stepanov Sergey, Makarov Oleg, Hilgart Mark, Pothineni Sudhir Babu, Urakhchin Alex, Devarapalli Satish, Yoder Derek, Becker Michael, Ogata Craig, Sanishvili Ruslan, Venugopalan Nagarajan, Smith Janet L, Fischetti Robert F
GM/CA-CAT at the APS, Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439, USA.
Acta Crystallogr D Biol Crystallogr. 2011 Mar;67(Pt 3):176-88. doi: 10.1107/S0907444910053916. Epub 2011 Feb 15.
The trio of macromolecular crystallography beamlines constructed by the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA-CAT) in Sector 23 of the Advanced Photon Source (APS) have been in growing demand owing to their outstanding beam quality and capacity to measure data from crystals of only a few micrometres in size. To take full advantage of the state-of-the-art mechanical and optical design of these beamlines, a significant effort has been devoted to designing fast, convenient, intuitive and robust beamline controls that could easily accommodate new beamline developments. The GM/CA-CAT beamline controls are based on the power of EPICS for distributed hardware control, the rich Java graphical user interface of Eclipse RCP and the task-oriented philosophy as well as the look and feel of the successful SSRL BluIce graphical user interface for crystallography. These beamline controls feature a minimum number of software layers, the wide use of plug-ins that can be written in any language and unified motion controls that allow on-the-fly scanning and optimization of any beamline component. This paper describes the ways in which BluIce was combined with EPICS and converted into the Java-based JBluIce, discusses the solutions aimed at streamlining and speeding up operations and gives an overview of the tools that are provided by this new open-source control system for facilitating crystallographic experiments, especially in the field of microcrystallography.
由普通医学与癌症研究所协作访问团队(GM/CA-CAT)在先进光子源(APS)23区建造的三条大分子晶体学光束线,因其出色的光束质量以及测量仅几微米大小晶体数据的能力,需求不断增长。为充分利用这些光束线的先进机械和光学设计,已投入大量精力设计快速、便捷、直观且强大的光束线控制系统,使其能够轻松适应新的光束线发展。GM/CA-CAT光束线控制系统基于EPICS的分布式硬件控制能力、Eclipse RCP丰富的Java图形用户界面、面向任务的理念以及成功的SSRL BluIce晶体学图形用户界面的外观和感觉。这些光束线控制系统具有最少的软件层、广泛使用可采用任何语言编写的插件以及统一的运动控制,允许对任何光束线组件进行实时扫描和优化。本文描述了将BluIce与EPICS结合并转换为基于Java的JBluIce的方式,讨论了旨在简化和加速操作的解决方案,并概述了这个新的开源控制系统提供的用于促进晶体学实验,特别是在微晶学领域的工具。