Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study.
作者信息
Howes O, Bose S, Turkheimer F, Valli I, Egerton A, Stahl D, Valmaggia L, Allen P, Murray R, McGuire P
出版信息
Mol Psychiatry. 2011 Sep;16(9):885-6. doi: 10.1038/mp.2011.20. Epub 2011 Mar 1.
Abstract
摘要
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Presynaptic regulation of dopamine transmission in schizophrenia.精神分裂症中多巴胺传递的突触前调节。
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Elevated striatal dopamine function linked to prodromal signs of schizophrenia.纹状体多巴胺功能升高与精神分裂症前驱症状有关。
Arch Gen Psychiatry. 2009 Jan;66(1):13-20. doi: 10.1001/archgenpsychiatry.2008.514.
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Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America.北美高临床风险青年期精神病的预测：一项多中心纵向研究
Arch Gen Psychiatry. 2008 Jan;65(1):28-37. doi: 10.1001/archgenpsychiatry.2007.3.
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Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis.精神病中纹状体多巴胺能系统的分子成像研究及精神病前驱期的预测
Br J Psychiatry Suppl. 2007 Dec;51:s13-8. doi: 10.1192/bjp.191.51.s13.
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The role of dopamine for the pathophysiology of schizophrenia.多巴胺在精神分裂症病理生理学中的作用。
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Deconstructing psychosis with human brain imaging.利用人脑成像剖析精神病
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Molecular brain imaging and the neurobiology and genetics of schizophrenia.分子脑成像与精神分裂症的神经生物学和遗传学
Pharmacopsychiatry. 2003 Nov;36 Suppl 3:S152-7. doi: 10.1055/s-2003-45123.
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