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腹腔镜袖状胃切除术作为一种治疗病态肥胖的单阶段手术,其治疗效果包括生活质量的改善、合并症的解决、食物耐受性的提高以及 6 年的减重效果。

Laparoscopic sleeve gastrectomy as a single-stage procedure for the treatment of morbid obesity and the resulting quality of life, resolution of comorbidities, food tolerance, and 6-year weight loss.

机构信息

Department of Digestive Surgery, Groeninge Hospital, President Kennedylaan 4, 8500, Kortrijk, Belgium.

出版信息

Surg Endosc. 2011 Aug;25(8):2498-504. doi: 10.1007/s00464-011-1572-x. Epub 2011 Feb 27.

DOI:10.1007/s00464-011-1572-x
PMID:21359900
Abstract

BACKGROUND

This retrospective study evaluated long-term weight loss, resolution of comorbidities, quality of life (QoL), and food tolerance after laparoscopic sleeve gastrectomy (LSG).

METHODS

Between January 2003 and July 2008, 102 patients underwent LSG as a sole bariatric operation. A retrospective review of a prospectively collected database was performed. Demographics, complications, and percentage of excess weight loss (%EWL) were determined. Quality of life was measured using Medical Outcomes Survey Short Form 36 (SF-36) and Bariatric Analysis and Reporting Outcome System (BAROS) questionnaires, which were sent to all patients. The food tolerance score (FTS) was determined and compared with that of nonobese subjects.

RESULTS

A total of 83 patients (81.4%) were eligible for follow-up evaluation. Their mean initial body mass index (BMI) was 39.3 kg/m(2). No major complications occurred. At a median follow-up point of 49 months (range, 17-80 months), the mean %EWL was 72.3% ± 29.3%. For the 23 patients who reached the 6-year follow-up point, the mean %EWL was 55.9% ± 25.55%. The mean BAROS score was 6.5 ± 2.1, and a "good" to "excellent" score was observed for 75 patients (90.4%). In the comparison of patients with a %EWL greater than 50% and those with a %EWL of 50% or less, the SF-36 scores were statistically different only for "physical functioning" and "general health perception." The mean FTS was 23.8, and 95.2% of the patients described their food tolerance as acceptable to excellent.

CONCLUSION

Laparoscopic sleeve gastrectomy is a safe and effective bariatric procedure, although a tendency for weight regain is noted after 5 years of follow-up evaluation. Resolution of comorbidity is comparable with that reported in the literature. The LSG procedure results in good to excellent health-related QoL. Food tolerance is lower for patients after LSG than for nonobese patients who had no surgery, but 95.2% described food tolerance as acceptable to excellent.

摘要

背景

本回顾性研究评估了腹腔镜袖状胃切除术(LSG)后的长期减重效果、合并症的缓解情况、生活质量(QoL)和食物耐受性。

方法

2003 年 1 月至 2008 年 7 月期间,102 例患者接受了 LSG 作为单一减重手术。对前瞻性收集的数据库进行了回顾性分析。确定了人口统计学数据、并发症和超重减轻百分比(%EWL)。使用医疗结局调查 36 项简短量表(SF-36)和减重分析和报告结局系统(BAROS)问卷来衡量生活质量,将问卷发送给所有患者。确定了食物耐受性评分(FTS)并与非肥胖受试者进行了比较。

结果

共有 83 例患者(81.4%)符合随访评估条件。他们的平均初始体重指数(BMI)为 39.3kg/m²。无重大并发症发生。在中位数为 49 个月(范围 17-80 个月)的随访点,平均%EWL 为 72.3%±29.3%。对于达到 6 年随访点的 23 例患者,平均%EWL 为 55.9%±25.55%。平均 BAROS 评分为 6.5±2.1,75 例患者(90.4%)的评分“好”至“优秀”。在%EWL 大于 50%和等于或小于 50%的患者之间的比较中,SF-36 评分仅在“身体功能”和“总体健康感知”方面存在统计学差异。平均 FTS 为 23.8,95.2%的患者表示他们的食物耐受性可接受至优秀。

结论

腹腔镜袖状胃切除术是一种安全有效的减重手术,尽管在 5 年的随访评估后存在体重反弹的趋势。合并症的缓解与文献报道的情况相当。LSG 手术可带来良好至优秀的健康相关 QoL。LSG 术后患者的食物耐受性低于未经手术的非肥胖患者,但 95.2%的患者表示食物耐受性可接受至优秀。

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