Department of Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands.
Surg Endosc. 2011 Aug;25(8):2492-7. doi: 10.1007/s00464-011-1571-y. Epub 2011 Feb 27.
Boerhaave's syndrome has a high mortality rate (14-40%). Surgical treatment varies from a minimal approach consisting of adequate debridement with drainage of the mediastinum and pleural cavity to esophageal resection. This study compared the results between a previously preferred open minimal approach and a video-assisted thoracoscopic surgery (VATS) procedure currently considered the method of choice.
In this study, 12 consecutive patients treated with a historical nonresectional drainage approach (1985-2001) were compared with 12 consecutive patients treated prospectively after the introduction of VATS during the period 2002-2009. Baseline characteristics were equally distributed between the two groups.
In the prospective group, 2 of the 12 patients had the VATS procedure converted to an open thoracotomy, and 2 additional patients were treated by open surgery. In the prospective group, 8 patients experienced postoperative complications compared with all 12 patients in the historical control group. Four patients (17%), two in each group, underwent reoperation. Six patients, three in each group, were readmitted to the hospital. The overall in-hospital mortality was 8% (1 patient in each group), which compares favorably with other reports (7-27%) based on drainage alone.
Adequate surgical debridement with drainage of the mediastinum and pleural cavity resulted in a low mortality rate. The results for VATS in this relatively small series were comparable with those for an open thoracotomy.
Boerhaave 综合征的死亡率较高(14-40%)。手术治疗的方法多种多样,从彻底清创、纵隔和胸腔引流的最小程度方法到食管切除术。本研究比较了先前首选的开放最小程度方法和目前被认为是首选方法的电视辅助胸腔镜手术(VATS)之间的结果。
本研究比较了 12 例连续接受历史上非切除性引流方法(1985-2001 年)治疗的患者与 12 例连续接受 VATS 治疗的患者,VATS 在 2002-2009 年期间引入。两组患者的基线特征分布均匀。
在前瞻性组中,12 例患者中有 2 例 VATS 手术转为开胸手术,另有 2 例患者接受了开胸手术。在前瞻性组中,有 8 例患者发生术后并发症,而历史对照组中有 12 例患者发生术后并发症。4 例患者(17%),每组 2 例,需要再次手术。6 例患者(每组 3 例)需要再次住院。总的院内死亡率为 8%(每组 1 例),与其他仅基于引流的报告(7-27%)相比,这一死亡率较低。
充分的纵隔和胸腔引流清创术可降低死亡率。本研究中相对较小的 VATS 系列结果与开胸手术相当。