Dicello John F, Gersey Bradford B, Gridley Daila S, Coutrakon George B, Lesyna David, Pisacane Vincent L, Robertson James B, Schulte Reinhard W, Slater Jerry D, Wroe Andrew J, Slater James M
Department of Radiation Medicine, Loma Linda University Medical Center, 25 Westminster Bridge Way, Timonium, MD, USA.
Radiat Prot Dosimetry. 2011 Feb;143(2-4):513-8. doi: 10.1093/rpd/ncq513.
Multiple groups have hypothesised that the use of scanning beams in proton therapy will reduce the neutron component of secondary radiation in comparison with conventional methods with a corresponding reduction in risks of radiation-induced cancers. Loma Linda University Medical Center (LLUMC) has had FDA marketing clearance for scanning beams since 1988 and an experimental scanning beam has been available at the LLUMC proton facility since 2001. The facility has a dedicated research room with a scanning beam and fast switching that allows its use during patient treatments. Dosimetric measurements and microdosimetric distributions for a scanned beam are presented and compared with beams produced with the conventional methods presently used in proton therapy.
多个研究小组推测，与传统方法相比，质子治疗中使用扫描束将减少二次辐射的中子成分，从而相应降低辐射诱发癌症的风险。自1988年以来，洛马林达大学医学中心（LLUMC）已获得美国食品药品监督管理局（FDA）对扫描束的市场许可，自2001年起，LLUMC质子治疗设施就有了实验性扫描束。该设施有一个配备扫描束和快速切换功能的专用研究室，使其能够在患者治疗期间使用。本文给出了扫描束的剂量测量和微剂量分布，并与目前质子治疗中使用的传统方法产生的束进行了比较。
