Isibasi A, Blanco F, Arreguín C, Martínez G, Pelayo R, Orozco E, Kumate J
Lab. de Inmunoquímica Unidad de Inv. biomédica, C.M.N., I.M.S.S., México, D.F.
Arch Invest Med (Mex). 1990;21 Suppl 1:175-81.
There probably exist many different surface molecular polysaccharides with different compositions of their constituent sugars, in the different zymodemes. This fact might have a repercussion upon the resistance to the lysis of the complement. Seeking to prove this hypothesis, the ideal would be to obtain polysaccharide molecules of type LPFG of pathogenic and non-pathogenic zymodemes, demonstrating that there is a difference in the chemical composition of their polysaccharides. If this were true, a serologic classification, of the different zymodemes, would be possible in a fashion similar to gram-negative bacteria. Our results suggest the existence of structural differences between the polysaccharides of a virulent clone (C-A) and a non-virulent one (L-6).
在不同的酶型中，可能存在许多不同的表面分子多糖，其组成糖的成分各异。这一事实可能会对补体裂解抗性产生影响。为了证明这一假设，理想的情况是获得致病和非致病酶型的LPFG型多糖分子，以证明它们多糖的化学成分存在差异。如果这是真的，那么就有可能以类似于革兰氏阴性菌的方式对不同的酶型进行血清学分类。我们的结果表明，有毒力克隆（C-A）和无毒力克隆（L-6）的多糖之间存在结构差异。
