[格但斯克大学医学中心所见的高安动脉炎的临床表现]
[Clinical manifestations of Takayasu's arteritis seen at the University Medical Center in Gdańsk].
作者信息
Czuszyńska Zenobia, Zdrojewski Zbigniew
机构信息
Katedra i Klinika Chorób Wewnetrznych, Chorób Tkanki Łacznej i Geriatrii Gdańskiego Uniwersytetu Medycznego ul. Debinki 7, 80-952 Gdańsk.
出版信息
Ann Acad Med Stetin. 2010;56 Suppl 1:95-8.
INTRODUCTION
Takayasu's arteritis (TA) is a granulomatous inflammation of the aorta and its major branches, usually occurring in young women. The disease is rare in Europe. The aim of this study was to describe clinical manifestations of TA among patients at the Department of Connective Tissue Diseases, University Medical Center in Gdańsk.
MATERIAL AND METHODS
We conducted a retrospective data analysis and performed a clinical examination of the patients. All patients met ACR criteria for TA. The mean age at disease onset was 26 years and the mean diagnostic delay was 19 months. Four out of 12 patients had a history of extensive stroke. Bypass surgery or balloon angioplasty was done in four patients. One patient underwent aortic valve replacement.
CONCLUSION
Early diagnosis and pharmacologic treatment may significantly improve the prognosis in TA.
引言
高安动脉炎（TA）是一种主动脉及其主要分支的肉芽肿性炎症，通常发生于年轻女性。该病在欧洲较为罕见。本研究的目的是描述格但斯克大学医学中心结缔组织病科患者中TA的临床表现。
材料与方法
我们进行了回顾性数据分析，并对患者进行了临床检查。所有患者均符合TA的美国风湿病学会（ACR）标准。疾病发病的平均年龄为26岁，平均诊断延迟为19个月。12例患者中有4例有广泛中风病史。4例患者接受了搭桥手术或球囊血管成形术。1例患者接受了主动脉瓣置换术。
结论
早期诊断和药物治疗可能显著改善TA的预后。
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