Digestive Department, Virgen Macarena University Hospital, Seville, Spain.
Rev Esp Enferm Dig. 2011 Feb;103(2):69-75. doi: 10.4321/s1130-01082011000200004.
several studies have pointed out the effectiveness of the PillCam colon capsule endoscopy (CCE) compared with the colonoscopy in the study of the colonic pathology.
the objective of our study was to assess the agreement in the diagnosis of CCE with conventional colonoscopy as well as its sensitivity and specificity, and to describe the findings of the CCE in our clinical practice. Consecutive patients with abdominal symptoms were included in the study. The CCE was performed as previously reported (with PEG and sodium phosphate as laxative agents). The nature and location of the findings, colonic transit time, complications, cleanliness degree and consistency with diagnostic colonoscopy, when performed, were analyzed.
a total of 144 subjects (67 women and 77 men); (52.17 ± 16.71 years) with the following indications were included: screening of Colorectal cancer (88 patients), control after polipectomy (24), incomplete colonoscopy (7), rectal bleeding (10), anemia (8), diarrhea (7). The CCE exploration was complete in 134/144 cases (93%), with no case of retention. The preparation was good-very good in 88/134 (65,6%), fair in 26/134 (19,4%) and poor in 20/134 (15%) of the cases. The average colonic transit was of 140.76 min (9-603). Any adverse effect was notified.In 44 cases a colonoscopy was carried out after CCE (results were hidden from another endoscopist). Compared to colonoscopy, the rate of agreement was 75,6%, the sensitivity was 84% and the specificity 62,5%, PPV was 77,7% and NPV was 71,4%.The colonic findings in 134 CCE were: in 34 cases CCE it did not show lesions, diverticulosis in 63 explorations, polyps in 43, angiodysplasias in 15, Crohn's Disease in 9 and ulcerative colitis in other 8 cases.
the CCE is an effective and reliable technique for the detection of lesions in colon, and because of its high agreement with the colonoscopy, it could be useful in clinical practice. Further studies with large seria and cost-effectiveness analysis are needed to confirm these data.
几项研究指出，与结肠镜检查相比，PillCam 结肠胶囊内镜（CCE）在结肠病理学研究中的有效性。
我们研究的目的是评估 CCE 与常规结肠镜检查诊断的一致性及其敏感性和特异性，并描述我们临床实践中 CCE 的发现。连续出现腹部症状的患者纳入研究。CCE 如前所述进行（PEG 和磷酸钠作为泻药）。分析发现的性质和位置、结肠通过时间、并发症、清洁度以及与进行的诊断性结肠镜检查的一致性。
共纳入 144 例患者（67 例女性和 77 例男性）；（52.17±16.71 岁）具有以下指征：结直肠癌筛查（88 例）、息肉切除后随访（24 例）、结肠镜检查不完全（7 例）、直肠出血（10 例）、贫血（8 例）、腹泻（7 例）。144 例中的 134 例（93%）完成了 CCE 检查，无保留病例。准备情况良好（65.6%）、良好（26.1%）、差（15%）。平均结肠通过时间为 140.76 分钟（9-603 分钟）。任何不良影响均有通知。44 例 CCE 后行结肠镜检查（结果对另一位内镜医生保密）。与结肠镜检查相比，一致性率为 75.6%，敏感性为 84%，特异性为 62.5%，PPV 为 77.7%，NPV 为 71.4%。134 例 CCE 的结肠发现：34 例 CCE 未见病变，63 例检查发现憩室病，43 例发现息肉，15 例发现血管发育不良，9 例发现克罗恩病，8 例发现溃疡性结肠炎。
CCE 是一种检测结肠病变的有效可靠技术，由于与结肠镜检查高度一致，因此在临床实践中可能有用。需要进一步进行大系列和成本效益分析的研究来证实这些数据。
