Barr Ronald, Collins Laura, Nayiager Trishana, Doring Nancy, Kennedy Charlene, Halton Jacqueline, Walker Scott, Sala Alessandra, Webber Colin
Department of Pediatrics, Faculty of Health Sciences, McMaster University, Ottawa, Ontario, Canada.
J Pediatr Hematol Oncol. 2011 Apr;33(3):e101-4. doi: 10.1097/MPH.0b013e3182002a65.
Assessment of nutritional status in children with cancer is important but measures based on weight can be problematic at diagnosis, especially in those with advanced disease. Likewise, dual energy x-ray absorptiometry may be confounded by other radiological procedures and is not commonly available in low-income countries where most children with cancer live. Arm anthropometry is not subject to these constraints. In a study sample of 99 Canadian patients with cancer at diagnosis, mid-upper arm circumference correlated well with lean body mass as measured by dual energy x-ray absorptiometry but triceps skin fold thickness was a poor predictor of fat mass. Arm anthropometry can be a useful tool for the measurement of nutritional status in children with cancer. However, further studies, particularly in low-income countries and in children with solid tumors at diagnosis, are required to determine the full extent of its utility.
评估癌症患儿的营养状况很重要,但基于体重的测量方法在诊断时可能存在问题,尤其是对于患有晚期疾病的患儿。同样,双能X线吸收法可能会受到其他放射学检查的干扰,而且在大多数癌症患儿居住的低收入国家并不常用。上臂人体测量不受这些限制。在一项对99名加拿大癌症确诊患者的研究样本中,上臂中部周长与双能X线吸收法测量的瘦体重相关性良好,但肱三头肌皮褶厚度对脂肪量的预测能力较差。上臂人体测量可以作为评估癌症患儿营养状况的有用工具。然而,需要进一步研究,特别是在低收入国家以及诊断为实体瘤的患儿中进行研究,以确定其全部效用范围。