慢性多灶性 Q 热骨髓炎的成功治疗：辅助使用干扰素-γ疗法。

Successful management of chronic multifocal Q fever Osteomyelitis with adjuvant interferon-gamma therapy.

机构信息

Division of Pediatric Infectious Diseases, Hospital Universitario Infantil Virgen del Rocio, Sevilla, Spain.

出版信息

Pediatr Infect Dis J. 2011 Sep;30(9):810-2. doi: 10.1097/INF.0b013e31821487f5.

Abstract

We present a 3-year-old girl who had chronic recurrent multifocal osteomyelitis caused by Coxiella burnetii despite long-term dual antibiotic therapy. Excellent clinical response was achieved and sustained when immunomodulatory therapy with interferon-γ was initiated. This is the case of a first child who was successfully treated with interferon-γ as adjuvant therapy for chronic multifocal Q fever osteomyelitis.

摘要

我们报告了一例 3 岁女童，尽管长期接受双联抗生素治疗，但仍患有慢性复发性多灶性骨髓炎，由贝纳柯克斯体引起。当开始使用干扰素-γ进行免疫调节治疗时，获得了出色的临床反应并得以持续。这是首例成功用干扰素-γ作为辅助治疗慢性多灶性 Q 热骨髓炎的患儿。