Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA.
Am J Obstet Gynecol. 2011 Mar;204(3):265.e1-5. doi: 10.1016/j.ajog.2010.12.009.
The purpose of this study was to investigate the association between large-for-gestational-age (LGA) infants and the development of childhood obesity in an inner-city primarily African American population.
Maternal, neonatal, socioeconomic, and nutritional histories were collected for mothers with children who were 2-5 years old. Associations between Alexander and customized birthweight percentiles and body mass index for the age of the child were examined.
One hundred ninety-five mother-child pairs were enrolled; the childhood obesity rate was 18%. Increasing Alexander and customized birthweight percentiles were related to increasing obesity. LGA newborn infants were 2.5 times more likely to be obese in childhood than average size newborn infants. Maternal smoking was also associated with childhood obesity.
LGA infants have the highest likelihood of childhood obesity in this inner-city predominantly African American population. Customized growth percentiles perform best in the identification of the highest risk population.
本研究旨在调查在一个以非洲裔美国人为主的市中心人群中,巨大儿(LGA)婴儿与儿童期肥胖发展之间的关系。
为 2-5 岁儿童的母亲收集了母亲、新生儿、社会经济和营养史。检查了亚历山大和定制出生体重百分位数与儿童年龄的体重指数之间的关联。
共纳入 195 对母婴对,儿童肥胖率为 18%。亚历山大和定制出生体重百分位数的增加与肥胖的增加有关。与正常大小的新生儿相比,LGA 新生儿在儿童期肥胖的可能性高 2.5 倍。母亲吸烟也与儿童肥胖有关。
在这个以非洲裔美国人为主的市中心人群中,LGA 婴儿最有可能在儿童期肥胖。定制生长百分位数在确定高危人群方面表现最佳。