Oñoro G, Pérez Suárez E, Iglesias Bouzas M I, Serrano A, Martínez De Azagra A, García-Teresa M A, Casado Flores J
Servicio de Cuidados Intensivos Pediátricos, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
An Pediatr (Barc). 2011 Jun;74(6):371-6. doi: 10.1016/j.anpedi.2011.01.012. Epub 2011 Mar 3.
Bronchiolitis generates lots of admissions during the cold months in the paediatric intensive care units (PICU). New forms of respiratory support are being used and could improve the care of these patients.
To analyse the epidemiological and respiratory support changes of children admitted to the PICU.
An observational, retrospective, descriptive and analytical study of patients with the diagnosis of bronchiolitis admitted to the PICU of a tertiary hospital during the respiratory syncytial virus (RSV) epidemic months between 2005 and 2010.
A total of 229 patients were admitted, of whom 83% were infected with RSV. The mean age was 1.48 months, with children under 3 months being the greatest number of admissions (73.3%). December was the month with the highest number of admissions (52%). Mortality was 0.9%. The mean time of stay in the PICU and on respiratory assistance were 4 and 3 days, respectively (no significant differences between the periods studied). Patients with RSV bronchiolitis were younger than the negative RSV (mean 2.61 months and 4.05 months, P=.023). Active respiratory support was required in 73% of cases. The percentage of patients who required active respiratory support increased over the years (Z=3.81, P=.00014), especially high flow nasal oxygen therapy (Z=3.62, P=.00028). An inverse relationship was observed between patient age and length of stay in PICU (Beta=-0.245, P ≤.0001) and days on respiratory support (Beta=-0.167, P=.039).
Most patients admitted to the PICU are less than 3 months old. Mortality was 0.9%. Respiratory support (especially non-invasive mechanical ventilation and high flow nasal oxygen therapy) is used increasingly often. The youngest patients need more days in PICU and more respiratory support.
毛细支气管炎在儿科重症监护病房(PICU)的寒冷月份导致大量患儿入院。新型呼吸支持方式正在被应用,有望改善这些患者的治疗效果。
分析入住PICU的儿童的流行病学特征及呼吸支持方式的变化。
对一家三级医院PICU在2005年至2010年呼吸道合胞病毒(RSV)流行月份收治的毛细支气管炎确诊患者进行观察性、回顾性、描述性及分析性研究。
共收治229例患者,其中83%感染RSV。平均年龄为1.48个月,3个月以下儿童入院人数最多(73.3%)。12月入院人数最多(52%)。死亡率为0.9%。在PICU的平均住院时间和接受呼吸支持的平均时间分别为4天和3天(各研究时间段之间无显著差异)。RSV毛细支气管炎患者比RSV阴性患者年龄更小(平均分别为2.61个月和4.05个月,P = 0.023)。73%的病例需要积极的呼吸支持。多年来需要积极呼吸支持的患者比例有所增加(Z = 3.81,P = 0.00014),尤其是高流量鼻导管给氧疗法(Z = 3.62,P = 0.00028)。观察到患者年龄与在PICU的住院时间(β = -0.245,P≤0.0001)及呼吸支持天数(β = -0.167,P = 0.039)之间呈负相关。
入住PICU的大多数患者年龄小于3个月。死亡率为0.9%。呼吸支持(尤其是无创机械通气和高流量鼻导管给氧疗法)的使用越来越频繁。年龄最小的患者在PICU需要更长时间及更多的呼吸支持。