Ikarashi Yoshiaki, Uchino Tadashi, Nishimura Tetsuji
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2010(128):85-90.
Preservatives are used to inhibit the growth of microorganisms in cosmetic products. The Japanese standards for cosmetics set restrictions on the maximum amount of each preservative added to cosmetics as per the purpose of use of cosmetics. For the investigation into the actual conditions of commonly used preservatives in commercial cosmetics, we analyzed parabens, phenoxyethanol, sodium benzoate, sodium dehydroacetate, salicylic acid, and potassium sorbate by high-performance liquid chromatography (HPLC). Twenty-one samples were obtained from cosmetic product manufacturers located in 14 prefectures in Japan. Among different acid- and salt-based preservatives, sodium benzoate was observed to have been used in many products. These acid- and salt-based preservatives were used with parabens in personal washing products, such as shampoo and soap. The labels of two of the cosmetic product samples displayed inaccurate ingredient information, that is, a preservative other than the one used in the corresponding product was listed on them. The amount of preservatives used did not exceed regulatory limits in any of the analyzed samples.
防腐剂用于抑制化妆品中微生物的生长。日本化妆品标准根据化妆品的使用目的,对添加到化妆品中的每种防腐剂的最大用量设定了限制。为了调查市售化妆品中常用防腐剂的实际情况,我们采用高效液相色谱法(HPLC)分析了对羟基苯甲酸酯、苯氧乙醇、苯甲酸钠、脱氢乙酸钠、水杨酸和山梨酸钾。从日本14个县的化妆品制造商处获取了21个样品。在不同的酸类和盐类防腐剂中,观察到许多产品中都使用了苯甲酸钠。这些酸类和盐类防腐剂与对羟基苯甲酸酯一起用于洗发水和肥皂等个人洗涤产品中。其中两个化妆品样品的标签显示的成分信息不准确,即列出的防腐剂与相应产品中使用的防腐剂不符。在所有分析样品中,防腐剂的使用量均未超过监管限制。