Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Centennial Building, 4th floor, 1685 Highland Avenue, Madison, WI 53705, United States.
Best Pract Res Clin Gastroenterol. 2011 Feb;25(1):19-27. doi: 10.1016/j.bpg.2010.12.004.
This review summarises the literature on quality of life (QOL) assessments in both children and adults with functional constipation. Studies of adults with constipation include subjects from both tertiary care centres and population-based surveys whereas there are no population-based studies in children. The preponderance of evidence indicates that the adverse effects of chronic constipation on QOL in both children and adults are comparable to that seen in other chronic gastrointestinal and non-gastrointestinal disorders. There are no data on the effect of treatment of children with constipation with regard to QOL whereas several studies indicate that successful treatment of constipation in adults has a favourable effect on QOL. The emerging concept in the treatment of chronic constipation is to measure both objective measures such as frequency and ease of defecation and subjective parameters such as QOL.
这篇综述总结了功能性便秘儿童和成人生活质量（QOL）评估方面的文献。成人便秘研究包括来自三级保健中心和基于人群的调查的受试者，而儿童则没有基于人群的研究。大多数证据表明，慢性便秘对儿童和成人 QOL 的不良影响与其他慢性胃肠道和非胃肠道疾病相当。目前还没有关于治疗儿童便秘对 QOL 影响的数据，而有几项研究表明，成功治疗成人便秘对 QOL 有积极影响。在慢性便秘的治疗中出现的新概念是测量客观指标，如排便频率和排便难易程度以及主观参数，如 QOL。
