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针刺对绝经症状和生殖激素的影响:一项假对照临床试验。

The effect of acupuncture on postmenopausal symptoms and reproductive hormones: a sham controlled clinical trial.

机构信息

Department of Family Medicine, Ministry of Health, Ankara Training and Research Hospital, Kız kulesi sokak 3/5 Gaziosmanpasa Çankaya, Ankara, Turkey.

出版信息

Acupunct Med. 2011 Mar;29(1):27-31. doi: 10.1136/aim.2010.003285.

DOI:10.1136/aim.2010.003285
PMID:21383392
Abstract

BACKGROUND

Acupuncture is commonly used to treat menopausal symptoms and other gynaecological conditions. In this study, the authors aimed to investigate whether acupuncture has an effect on menopausal symptoms and to explore whether this effect is related to changes in hormone levels. Materials and methods A total of 53 postmenopausal women were alternately assigned into two treatment groups: acupuncture (n=27) and sham acupuncture (n=26). Menopausal symptoms were assessed using the Menopause Rating Scale (MRS). The serum oestradiol, follicular stimulating hormone (FSH) and luteinising hormone (LH) levels were measured at baseline and again after the first and last sessions. The Student t test was used for normally distributed data and the Wilcoxon signed rank test for not normally distributed data. The group differences in MRS scores were assessed using non-parametric Mann-Whitney U test.

RESULTS

After treatment, total MRS, and the somatic and psychological subscale scores were significantly lower in the acupuncture group than the sham group (all p=0.001). The severity of hot flushes was found to be significantly decreased after treatment in acupuncture group (p=0.001). In the acupuncture group LH levels were lower and oestradiol levels were significantly higher than sham group (p=0.046 and p=0.045, respectively) after treatment, but there was no difference in FSH levels.

CONCLUSION

Acupuncture was effective in reducing menopausal complaints when compared to sham acupuncture and can be considered as an alternative therapy in the treatment of menopausal symptoms.

摘要

背景

针灸常用于治疗更年期症状和其他妇科疾病。本研究旨在探讨针灸是否对更年期症状有影响,以及这种影响是否与激素水平的变化有关。

材料和方法

共有 53 名绝经后妇女被交替分配到两组治疗中:针灸组(n=27)和假针灸组(n=26)。采用更年期症状评定量表(MRS)评估更年期症状。在基线、第一次和最后一次治疗后测量血清雌二醇、卵泡刺激素(FSH)和黄体生成素(LH)水平。正态分布数据采用学生 t 检验,非正态分布数据采用 Wilcoxon 符号秩检验。采用非参数 Mann-Whitney U 检验评估 MRS 评分的组间差异。

结果

治疗后,针灸组的总 MRS 评分以及躯体和心理子量表评分均明显低于假针灸组(均 p=0.001)。治疗后,针灸组的潮热严重程度明显降低(p=0.001)。治疗后,针灸组的 LH 水平低于假针灸组,雌二醇水平明显高于假针灸组(p=0.046 和 p=0.045),但 FSH 水平无差异。

结论

与假针灸相比,针灸在减轻更年期不适方面更有效,可以作为治疗更年期症状的替代疗法。

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