Bamanie Afaf H, Al-Noury Khaled I
Department of Otolaryngology, Head & Neck Surgery, King Abdulaziz University, PO Box 35135, Jeddah 21488, Kingdom of Saudi Arabia.
Saudi Med J. 2011 Mar;32(3):271-4.
To compare hearing impairment and audiometric shapes associated with type 2 diabetes mellitus (T2DM) with an age-matched control group in the Saudi population.
This is an observational case-control study at a tertiary academic referral center. We recruited 196 individuals (age; 29-69 years) attending the Department of Otolaryngology, King Abdulaziz University Hospital between January 2005 to December 2009, and grouped them into T2DM (n=109) and control (n=87) groups. We excluded patients with a history of noise exposure, conductive hearing loss, ototoxic medications, and a positive family history of hearing impairment. Age, gender, family history, duration of T2DM, current treatment, and presence of diabetic complications were noted. Pure tone hearing (in decibels [dB])was recorded. Data were statistically analyzed against the matched control group.
We identified a strong relationship between T2DM and low and mid frequencies hearing loss than the matched controls. A flat audiogram was the most common audiometric shape observed. Patients with associated diabetic complications were at a higher risk of hearing loss, while hyperglycemic control by insulin was also observed to be a risk factor for hearing loss.
The T2DM is strongly associated with hearing loss especially in the low and mid frequencies. Several factors including age, diabetes control by insulin, and presence of complications, may be risk factors for hearing loss in DM patients.
在沙特人群中，将2型糖尿病（T2DM）患者的听力损害及听力图形状与年龄匹配的对照组进行比较。
这是一项在三级学术转诊中心开展的观察性病例对照研究。我们招募了196名年龄在29至69岁之间、于2005年1月至2009年12月期间在阿卜杜勒阿齐兹国王大学医院耳鼻喉科就诊的患者，并将他们分为T2DM组（n = 109）和对照组（n = 87）。我们排除了有噪声暴露史、传导性听力损失、耳毒性药物使用史以及听力损害家族史阳性的患者。记录了年龄、性别、家族史、T2DM病程、当前治疗情况以及糖尿病并发症的存在情况。记录了纯音听力（以分贝[dB]为单位）。针对匹配的对照组对数据进行了统计分析。
我们发现，与匹配的对照组相比，T2DM与低频和中频听力损失之间存在密切关系。平坦型听力图是观察到的最常见的听力图形状。伴有糖尿病并发症的患者听力损失风险更高，同时还观察到胰岛素控制血糖也是听力损失的一个风险因素。
T2DM与听力损失密切相关，尤其是在低频和中频。包括年龄、胰岛素控制糖尿病以及并发症的存在等几个因素可能是糖尿病患者听力损失的风险因素。
