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药剂师与医生的合作可改善血压控制。

Pharmacist-physician collaboration improves blood pressure control.

作者信息

Albsoul-Younes Abla M, Hammad Eman A, Yasein Nada A, Tahaineh Linda M

机构信息

Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, University of Jordan, Amman, Jordan.

出版信息

Saudi Med J. 2011 Mar;32(3):288-92.

Abstract

OBJECTIVE

To evaluate the effect of teamwork (physician and pharmacist) on the management of uncontrolled hypertensive patients.

METHODS

This is a randomized controlled clinical trial conducted from March to November 2009. Patients attending the Family Medicine Clinic at Jordan University Hospital, Amman, Jordan with uncontrolled hypertension were invited to participate in the study. A total of 253 patients were randomly allocated to an intervention (n=130) or control group. In the intervention group, patients were managed by a physician-pharmacist team. In the control group, patients were managed by physician(s) only.

RESULTS

In the intervention group, 79.4% of patients achieved blood pressure (BP) goals specified by the Joint National Committee on Prevention and Management, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VII) compared to 65.6% in the control group (p=0.01). Decline in systolic BP was 16.1 +/- 14.6 mm Hg in the intervention group, and 10.6 +/- 13.5 mm Hg in the control group (p=0.002). Reduction in diastolic BP was 10.5 +/- 12.9 mm Hg in the intervention group, and 7.17 +/- 13.11 mm Hg in the control group, (p=0.04). Data were presented as mean +/- standard deviation.

CONCLUSION

This study found that the physician-pharmacist collaborative approach to uncontrolled hypertension in Jordan improved the rate of BP control in hypertensive patients, and resulted in more profound decline in both systolic and diastolic BP, and this will probably reflect on better outcomes in cardiovascular diseases. Establishing pharmaceutical care managed clinic in the setting of outpatient-clinics is possible, and provides better management of patients.

摘要

目的

评估团队合作(医生和药剂师)对血压控制不佳的高血压患者管理的效果。

方法

这是一项于2009年3月至11月进行的随机对照临床试验。邀请约旦安曼市约旦大学医院家庭医学诊所中血压控制不佳的患者参与研究。总共253名患者被随机分配至干预组(n = 130)或对照组。干预组患者由医生 - 药剂师团队管理。对照组患者仅由医生管理。

结果

干预组中,79.4%的患者达到了美国国家高血压预防、检测、评估与治疗联合委员会(JNC VII)规定的血压目标,而对照组为65.6%(p = 0.01)。干预组收缩压下降幅度为16.1±14.6 mmHg,对照组为10.6±13.5 mmHg(p = 0.002)。干预组舒张压下降幅度为10.5±12.9 mmHg,对照组为7.17±13.11 mmHg(p = 0.04)。数据以均值±标准差表示。

结论

本研究发现,约旦采用医生 - 药剂师协作方法管理血压控制不佳的高血压患者,可提高高血压患者的血压控制率,并使收缩压和舒张压均有更显著下降,这可能会反映在心血管疾病更好的治疗结果上。在门诊诊所环境中建立药学服务管理的诊所是可行的,并且能为患者提供更好的管理。

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