School of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa 920-1192, Japan.
Chemistry. 2011 Apr 4;17(15):4307-12. doi: 10.1002/chem.201003060. Epub 2011 Mar 7.
A mild and practical oxyarylation of alkenes by oxidative radical addition has been developed by using aerobic oxidation of hydrazine compounds. The use of a catalytic amount of potassium ferrocyanide trihydrate (K(4)[Fe(CN)(6)]⋅3H(2)O) and water accelerated this radical reaction to give peroxides or alcohols from simple alkenes in good yields. The environmentally friendly and economical radical reactions were achieved at room temperature in the presence of iron catalyst, oxygen gas, and water. A method involving aniline as a radical precursor is also described.
发展了一种通过肼类化合物的有氧氧化来实现的温和且实用的烯烃的氧芳基化方法。使用催化量的三水合三铁氰化钾（K(4)[Fe(CN)(6)]⋅3H(2)O）和水加速了该自由基反应，可从简单的烯烃以良好的收率得到过氧化物或醇。在室温下，在铁催化剂、氧气和水的存在下，实现了环保且经济的自由基反应。还描述了一种涉及苯胺作为自由基前体的方法。
